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EBOZM:L

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Species (Taxon ID) Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus). (128952)
Gene Name(s) L
Protein Name(s) RNA-directed RNA polymerase L

Protein L Large structural protein Replicase Transcriptase RNA-directed RNA polymerase mRNA (guanine-N(7)-)-methyltransferase mRNA guanylyltransferase

External Links
UniProt Q05318
EMBL X67110
AF272001
AF086833
L11365
AY142960
AF499101
RefSeq NP_066251.1
ProteinModelPortal Q05318
IntAct Q05318
GeneID 911824
Proteomes UP000007209
GO GO:0030430
GO:0019012
GO:0005524
GO:0004482
GO:0003968
InterPro IPR026890
IPR014023
IPR025786
IPR017235
Pfam PF14318
PF00946
PIRSF PIRSF037548
TIGRFAMs TIGR04198
PROSITE PS50526
PS51590

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0039697

negative stranded viral RNA transcription

PMID:9971816[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0039689

negative stranded viral RNA replication

PMID:9971816[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0106005

RNA 5'-cap (guanine-N7)-methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

complete

involved_in

GO:0106005

RNA 5'-cap (guanine-N7)-methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

complete

enables

GO:0004482

mRNA (guanine-N7-)-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

complete

involved_in

GO:0006139

nucleobase-containing compound metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017235

P

Seeded From UniProt

complete

involved_in

GO:0006370

7-methylguanosine mRNA capping

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017235

F

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

C

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.48

F

Seeded From UniProt

complete

enables

GO:0004482

mRNA (guanine-N7-)-methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.56

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0511

P

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0511

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946
UniProtKB-SubCell:SL-0274

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0032259

methylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

complete

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1035
UniProtKB-SubCell:SL-0381

C

Seeded From UniProt

complete

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0696

F

Seeded From UniProt

complete

involved_in

GO:0006370

7-methylguanosine mRNA capping

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0506

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Mühlberger, E et al. (1999) Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems. J. Virol. 73 2333-42 PubMed GONUTS page