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Category:GO:0004146 ! dihydrofolate reductase activity
name: dihydrofolate reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+." [EC:1.5.1.3]
synonym: "5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity" RELATED [EC:1.5.1.3]
synonym: "7,8-dihydrofolate reductase activity" RELATED [EC:1.5.1.3]
synonym: "DHFR" RELATED [EC:1.5.1.3]
synonym: "dihydrofolate reductase:thymidylate synthase activity" RELATED [EC:1.5.1.3]
synonym: "dihydrofolate reduction" EXACT []
synonym: "dihydrofolic acid reductase activity" RELATED [EC:1.5.1.3]
synonym: "dihydrofolic reductase activity" RELATED [EC:1.5.1.3]
synonym: "folic acid reductase activity" RELATED [EC:1.5.1.3]
synonym: "folic reductase activity" RELATED [EC:1.5.1.3]
synonym: "NADPH-dihydrofolate reductase activity" RELATED [EC:1.5.1.3]
synonym: "pteridine reductase:dihydrofolate reductase activity" RELATED [EC:1.5.1.3]
synonym: "tetrahydrofolate dehydrogenase activity" RELATED [EC:1.5.1.3]
synonym: "thymidylate synthetase-dihydrofolate reductase activity" RELATED [EC:1.5.1.3]
xref: EC:1.5.1.3
xref: MetaCyc:DIHYDROFOLATEREDUCT-RXN
xref: RHEA:15009
is_a: GO:0016646 ! oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
AmiGO
<GOterm>GO:0004146</GOterm>
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