VIBTL:B7VPW7

Species (Taxon ID)	Vibrio splendidus (strain LGP32) (Vibrio splendidus (strain Mel32)). (575788)
Gene Name(s)	dfrA (ECO:0000313 with EMBL:CAV19067.1)
Protein Name(s)	Dihydrofolate reductase type I (Trimethoprim resistance) (ECO:0000313 with EMBL:CAV19067.1)
External Links
UniProt	B7VPW7
EMBL	FM954972
RefSeq	YP_002417492.1
STRING	575788.VS_1884
EnsemblBacteria	CAV19067
GeneID	7161447
KEGG	vsp:VS_1884
PATRIC	20154375
eggNOG	COG0262
HOGENOM	HOG000040233
KO	K00287
OMA	PRVEYAR
OrthoDB	EOG6KT2V2
BioCyc	VSPL575788:GH64-1851-MONOMER
GO	GO:0004146 GO:0050661 GO:0006545 GO:0009165
Gene3D	3.40.430.10
InterPro	IPR012259 IPR024072 IPR017925 IPR001796
Pfam	PF00186
PRINTS	PR00070
SUPFAM	SSF53597
PROSITE	PS00075 PS51330

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004146	dihydrofolate reductase activity	PMID:19364337	ECO:0000315			F		Fig. 5B; a dfr deletion mutant displayed a larger area of inhibition and greater sensitivity to trimethoprim.	complete CACAO 4543
enables	GO:0004146	dihydrofolate reductase activity	PMID:19364337	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259 InterPro:IPR017925	F		Seeded From UniProt	complete
involved_in	GO:0006545	glycine biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012259	P		Seeded From UniProt	complete
involved_in	GO:0046654	tetrahydrofolate biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259	P		Seeded From UniProt	complete
enables	GO:0050661	NADP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012259	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259 InterPro:IPR017925	P		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.5.1.3	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
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References

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