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ECOLX:H4JXW8
Contents
| Species (Taxon ID) | Escherichia coli DEC2A. (868138) | |
| Gene Name(s) | folA (ECO:0000313 with EMBL:EHU33921.1) | |
| Protein Name(s) | Dihydrofolate reductase (ECO:0000256 with PIRNR:PIRNR000194) | |
| External Links | ||
| UniProt | H4JXW8 | |
| EMBL | AIFA01000029 | |
| ProteinModelPortal | H4JXW8 | |
| SMR | H4JXW8 | |
| BindingDB | H4JXW8 | |
| EnsemblBacteria | EHU33921 | |
| OMA | MCITHVE | |
| UniPathway | UPA00077 | |
| Proteomes | UP000004201 | |
| GO | GO:0004146 GO:0050661 GO:0006545 GO:0009165 GO:0006730 GO:0046654 | |
| Gene3D | 3.40.430.10 | |
| InterPro | IPR012259 IPR024072 IPR017925 IPR001796 | |
| Pfam | PF00186 | |
| PIRSF | PIRSF000194 | |
| PRINTS | PR00070 | |
| SUPFAM | SSF53597 | |
| PROSITE | PS00075 PS51330 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004146 |
dihydrofolate reductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004146 |
dihydrofolate reductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0006545 |
glycine biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006730 |
one-carbon metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0009165 |
nucleotide biosynthetic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016491 |
oxidoreductase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0046654 |
tetrahydrofolate biosynthetic process |
IEA: Inferred from Electronic Annotation |
UniPathway:UPA00077 |
P |
Seeded From UniProt |
|||
| GO:0050661 |
NADP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0055114 |
oxidation-reduction process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0004146 |
dihydrofolate reductase activity |
ISA: Inferred from Sequence Alignment |
PMID:26147643[1] UniProtKB:P0ABQ4
|
F |
Blastp results showed 100.0% sequence similarity, with an E-value of 1.1E-114. |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Oyen, D et al. (2015) Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway. J. Am. Chem. Soc. 137 9459-68 PubMed GONUTS page