BACAN:Q81R22

Species (Taxon ID)	Bacillus anthracis. (1392)
Gene Name(s)	dfrA (ECO:0000313 with EMBL:AAT31357.1)
Protein Name(s)	Dihydrofolate reductase (ECO:0000256 with PIRNR:PIRNR000194)
External Links
UniProt	Q81R22
EMBL	AE017334 AY569129 CP012519 LGCC01000030 LGCD01000024
RefSeq	WP_000637198.1
PDB	2KGK 2QK8 3DAT 3E0B 3FL8 3FL9 3JVX 3JW3 3JW5 3JWC 3JWF 3JWK 3JWM 3S9U 3SA1 3SA2 3SAI 4ELB 4ELE 4ELF 4ELG 4ELH
PDBsum	2KGK 2QK8 3DAT 3E0B 3FL8 3FL9 3JVX 3JW3 3JW5 3JWC 3JWF 3JWK 3JWM 3S9U 3SA1 3SA2 3SAI 4ELB 4ELE 4ELF 4ELG 4ELH
STRING	198094.BA_2237
ChEMBL	CHEMBL5270
DNASU	1085515
EnsemblBacteria	AAT31357 AJG28965 AJH87338
KEGG	banh:HYU01_11160 bar:GBAA_2237
eggNOG	ENOG4108YYV COG0262
KO	K00287
OMA	KDNDLPW
OrthoDB	EOG6KT2V2
BioCyc	ANTHRA:DFRA-MONOMER BANT260799:GJAJ-2151-MONOMER BANT261594:GJ7F-2226-MONOMER
BRENDA	1.5.1.3
UniPathway	UPA00077
Proteomes	UP000000594 UP000054520
GO	GO:0004146 GO:0046872 GO:0050661 GO:0006760 GO:0006545 GO:0009165 GO:0006730 GO:0046654
Gene3D	3.40.430.10
InterPro	IPR012259 IPR024072 IPR017925 IPR001796
Pfam	PF00186
PIRSF	PIRSF000194
PRINTS	PR00070
SUPFAM	SSF53597
PROSITE	PS00075 PS51330

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004146	dihydrofolate reductase activity	GO_REF:0000100	ECO:0000247		UniProtKB:A0A087LEM1	F		Blastp results showed the dihydrofolate reductase activity relating Bacillus anthracis and Bacillus Stearothermophilus with 100% identity, 100% query cover, and an e-value of 3.7E-37	complete CACAO 12003
involved_in	GO:0006760	folic acid-containing compound metabolic process	PMID:12721629	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P11045	P		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity	PMID:12721629	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P11045	F		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259 InterPro:IPR017925	F		Seeded From UniProt	complete
involved_in	GO:0006545	glycine biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012259	P		Seeded From UniProt	complete
involved_in	GO:0046654	tetrahydrofolate biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259	P		Seeded From UniProt	complete
enables	GO:0050661	NADP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012259	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259 InterPro:IPR017925	P		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.5.1.3	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0006730	one-carbon metabolic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0554	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
involved_in	GO:0046654	tetrahydrofolate biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00077	P		Seeded From UniProt	complete
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References

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