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BACAN:Q81R22

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Species (Taxon ID) Bacillus anthracis. (1392)
Gene Name(s) dfrA (ECO:0000313 with EMBL:AAT31357.1)
Protein Name(s) Dihydrofolate reductase (ECO:0000256 with PIRNR:PIRNR000194)
External Links
UniProt Q81R22
EMBL AE017334
AY569129
CP012519
LGCC01000030
LGCD01000024
RefSeq WP_000637198.1
PDB 2KGK
2QK8
3DAT
3E0B
3FL8
3FL9
3JVX
3JW3
3JW5
3JWC
3JWF
3JWK
3JWM
3S9U
3SA1
3SA2
3SAI
4ELB
4ELE
4ELF
4ELG
4ELH
PDBsum 2KGK
2QK8
3DAT
3E0B
3FL8
3FL9
3JVX
3JW3
3JW5
3JWC
3JWF
3JWK
3JWM
3S9U
3SA1
3SA2
3SAI
4ELB
4ELE
4ELF
4ELG
4ELH
STRING 198094.BA_2237
ChEMBL CHEMBL5270
DNASU 1085515
EnsemblBacteria AAT31357
AJG28965
AJH87338
KEGG banh:HYU01_11160
bar:GBAA_2237
eggNOG ENOG4108YYV
COG0262
KO K00287
OMA KDNDLPW
OrthoDB EOG6KT2V2
BioCyc ANTHRA:DFRA-MONOMER
BANT260799:GJAJ-2151-MONOMER
BANT261594:GJ7F-2226-MONOMER
BRENDA 1.5.1.3
UniPathway UPA00077
Proteomes UP000000594
UP000054520
GO GO:0004146
GO:0046872
GO:0050661
GO:0006760
GO:0006545
GO:0009165
GO:0006730
GO:0046654
Gene3D 3.40.430.10
InterPro IPR012259
IPR024072
IPR017925
IPR001796
Pfam PF00186
PIRSF PIRSF000194
PRINTS PR00070
SUPFAM SSF53597
PROSITE PS00075
PS51330

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004146

dihydrofolate reductase activity

GO_REF:0000100

ECO:0000247

UniProtKB:A0A087LEM1


F

Blastp results showed the dihydrofolate reductase activity relating Bacillus anthracis and Bacillus Stearothermophilus with 100% identity, 100% query cover, and an e-value of 3.7E-37

complete
CACAO 12003

involved_in

GO:0006760

folic acid-containing compound metabolic process

PMID:12721629[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11045

P

Seeded From UniProt

complete

enables

GO:0004146

dihydrofolate reductase activity

PMID:12721629[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P11045

F

Seeded From UniProt

complete

enables

GO:0004146

dihydrofolate reductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001796
InterPro:IPR012259
InterPro:IPR017925

F

Seeded From UniProt

complete

involved_in

GO:0006545

glycine biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012259

P

Seeded From UniProt

complete

involved_in

GO:0046654

tetrahydrofolate biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001796
InterPro:IPR012259

P

Seeded From UniProt

complete

enables

GO:0050661

NADP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012259

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001796
InterPro:IPR012259
InterPro:IPR017925

P

Seeded From UniProt

complete

enables

GO:0004146

dihydrofolate reductase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.5.1.3

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0006730

one-carbon metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0554

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

involved_in

GO:0046654

tetrahydrofolate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00077

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Read, TD et al. (2003) The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria. Nature 423 81-6 PubMed GONUTS page