COXBU:Q83AB2

Species (Taxon ID)	Coxiella burnetii (strain RSA 493 / Nine Mile phase I). (227377)
Gene Name(s)	folA (ECO:0000313 with EMBL:AAO91482.1)
Protein Name(s)	Dihydrofolate reductase (ECO:0000256 with PIRNR:PIRNR000194)
External Links
UniProt	Q83AB2
EMBL	AE016828
RefSeq	NP_820968.1 WP_005769725.1
PDB	3TQ8 3TQ9 3TQA 3TQB
PDBsum	3TQ8 3TQ9 3TQA 3TQB
ProteinModelPortal	Q83AB2
STRING	227377.CBU_1993
PRIDE	Q83AB2
EnsemblBacteria	AAO91482
GeneID	1209906
KEGG	cbu:CBU_1993
PATRIC	17932727
eggNOG	ENOG4108YYV COG0262
HOGENOM	HOG000040233
KO	K00287
OMA	DTQFPDW
OrthoDB	EOG6KT2V2
BioCyc	CBUR227377:GJ7S-1966-MONOMER
UniPathway	UPA00077
Proteomes	UP000002671
GO	GO:0004146 GO:0050661 GO:0006545 GO:0009165 GO:0006730 GO:0046654
Gene3D	3.40.430.10
InterPro	IPR012259 IPR024072 IPR017925 IPR001796
Pfam	PF00186
PIRSF	PIRSF000194
PRINTS	PR00070
SUPFAM	SSF53597
PROSITE	PS00075 PS51330

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004146	dihydrofolate reductase activity	GO_REF:0000100	ECO:0000247		UniProtKB:A0A087LEM1	F		Blastp results showed the dihydrofolate reductase activity relating Bacillus phage Coxiella burnetii and Bacillus Stearothermophilus with 100% identity, 100% query cover, and an e-value of 6.4E-38	complete CACAO 12001
enables	GO:0050661	NADP binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000167322 RGD:2500	F		Seeded From UniProt	complete
involved_in	GO:0046655	folic acid metabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000167322 RGD:2500 ZFIN:ZDB-GENE-010406-5	P		Seeded From UniProt	complete
involved_in	GO:0046654	tetrahydrofolate biosynthetic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000167322 RGD:2500 UniProtKB:P00374 UniProtKB:P9WNX1	P		Seeded From UniProt	complete
involved_in	GO:0046452	dihydrofolate metabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000167322 RGD:2500 UniProtKB:P00374	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10326 PANTHER:PTN000167378	C		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10326 FB:FBgn0004087 MGI:MGI:94890 PANTHER:PTN000167322 PomBase:SPCC1223.08c RGD:2500 UniProtKB:P00374 UniProtKB:P9WNX1 UniProtKB:Q86XF0 dictyBase:DDB_G0286755	F		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259 InterPro:IPR017925	F		Seeded From UniProt	complete
involved_in	GO:0006545	glycine biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012259	P		Seeded From UniProt	complete
involved_in	GO:0046654	tetrahydrofolate biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259	P		Seeded From UniProt	complete
enables	GO:0050661	NADP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR012259	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001796 InterPro:IPR012259 InterPro:IPR017925	P		Seeded From UniProt	complete
enables	GO:0004146	dihydrofolate reductase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.5.1.3	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0006730	one-carbon metabolic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0554	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0046654	tetrahydrofolate biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00077	P		Seeded From UniProt	complete
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