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ENTFA:Q834R2

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Species (Taxon ID) Enterococcus faecalis (strain ATCC 700802 / V583). (226185)
Gene Name(s) folA (ECO:0000313 with EMBL:AAO81364.1)
Protein Name(s) Dihydrofolate reductase (ECO:0000256 with PIRNR:PIRNR000194)
External Links
UniProt Q834R2
EMBL AE016830
RefSeq NP_815294.1
WP_002360302.1
PDB 4M7U
4M7V
PDBsum 4M7U
4M7V
ProteinModelPortal Q834R2
STRING 226185.EF1577
EnsemblBacteria AAO81364
GeneID 1200477
KEGG efa:EF1577
PATRIC 21853510
eggNOG ENOG4108YYV
COG0262
KO K00287
OMA DTQFPDW
OrthoDB EOG6KT2V2
BioCyc EFAE226185:GHI1-1563-MONOMER
UniPathway UPA00077
Proteomes UP000001415
GO GO:0004146
GO:0050661
GO:0006545
GO:0009165
GO:0006730
GO:0046654
Gene3D 3.40.430.10
InterPro IPR012259
IPR024072
IPR017925
IPR001796
Pfam PF00186
PIRSF PIRSF000194
PRINTS PR00070
SUPFAM SSF53597
PROSITE PS00075
PS51330

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004146

dihydrofolate reductase activity

GO_REF:0000100

ECO:0000247

UniProtKB:A0A087LEM1


F

Blastp results showed the dihydrofolate reductase activity relating Enterococcus faecalis and Bacillus Stearothermophilus with 100% identity, 100% query cover, and an e-value of 7.2E-39

complete
CACAO 12002

enables

GO:0004146

dihydrofolate reductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001796
InterPro:IPR012259
InterPro:IPR017925

F

Seeded From UniProt

complete

involved_in

GO:0006545

glycine biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012259

P

Seeded From UniProt

complete

involved_in

GO:0046654

tetrahydrofolate biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001796
InterPro:IPR012259

P

Seeded From UniProt

complete

enables

GO:0050661

NADP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012259

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001796
InterPro:IPR012259
InterPro:IPR017925

P

Seeded From UniProt

complete

enables

GO:0004146

dihydrofolate reductase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.5.1.3

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

involved_in

GO:0006730

one-carbon metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0554

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0046654

tetrahydrofolate biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00077

P

Seeded From UniProt

complete

Notes

References

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