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User:Gamertmac

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableMOUSE:NK1R2011-09-25 15:29:58 CDTGO:0070472 positive regulation of uterine smooth muscle contraction (P)PMID:15647454ECO:0000314 direct assay evidence used in manual assertion

from figure 1 increasing amounts of NK1 were added to the uterine preparation prior to testing.

Contractile force produced by the longitudinally oriented smooth muscle fibers was recorded by a Grass FT03 force transducer connected to a MacLab data acquisition system. Uterine preparations treated with larger amounts of NK1 displayed increased levels of contraction.

challenge
acceptableMOUSE:NK2R2011-09-25 15:28:15 CDTGO:0070472 positive regulation of uterine smooth muscle contraction (P)PMID:15647454ECO:0000314 direct assay evidence used in manual assertion

from figure 1 increasing amounts of NK2 were added to the uterine preparation prior to testing. Contractile force produced by the longitudinally oriented smooth muscle fibers was recorded by a Grass FT03 force transducer connected to a MacLab data acquisition system. Uterine preparations treated with larger amounts of NK2 displayed increased levels of contraction.

challenge
acceptableMOUSE:SMTL12011-10-04 20:34:26 CDTGO:0016481 negative regulation of transcription (P)PMID:21771785ECO:0000314 direct assay evidence used in manual assertion

Proven in Figure 7B

challenge
acceptableMOUSE:PE2R22011-10-09 16:24:51 CDTGO:0032570 response to progesterone stimulus (P)PMID:10684792ECO:0000314 direct assay evidence used in manual assertion

Positive regulation shown in figure 4

challenge
acceptableMOUSE:PF2R2011-10-09 17:09:53 CDTGO:0032355 response to estradiol stimulus (P)PMID:10684792ECO:0000314 direct assay evidence used in manual assertion

Positive regulation to estradiol-17β from figure 7

challenge
acceptableMOUSE:PF2R2011-10-23 14:06:38 CDTGO:0010628 positive regulation of gene expression (P)PMID:21668646ECO:0000314 direct assay evidence used in manual assertion

Expression of COX-2 Figure 1 B

challenge
acceptableBOVIN:NEU12011-10-23 14:30:50 CDTGO:0043627 response to estrogen stimulus (P)PMID:21656645ECO:0000314 direct assay evidence used in manual assertion

Response to Coumesterol Figure 1B

challenge
acceptablePARDE:Q516662011-11-15 19:23:42 CSTGO:0016966 nitric oxide reductase activity (F)PMID:9022686ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2

challenge
acceptablePARDE:Q516672011-11-15 19:27:20 CSTGO:0016966 nitric oxide reductase activity (F)PMID:9022686ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2

challenge

acceptable:9
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Gamertmac

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
acceptableWwhitm2,
Team Step 2
PARDE:Q51665GO:0016966 - nitric oxide reductase activity (F)PMID:9022686ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableTaustin,
Team Big Mama 50000
HUMAN:M4K4GO:0046329 - negative regulation of JNK cascade (P)PMID:21196414ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3
unacceptableTaustin,
Team Big Mama 50000
HUMAN:M4K4GO:0097179 - protease inhibitor complex (C)PMID:21196414ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableVchhabria,
Team KremlinOnTheCrum
ECOL6:RCSFGO:0032494 - response to peptidoglycan (P)PMID:18192383ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
requireschangesVchhabria,
Team KremlinOnTheCrum
ECOL6:RCSFGO:0033554 - cellular response to stress (P)PMID:18192383ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
requireschangesOherrera,
Team That Will Beat You!!!
HUMAN:MK03GO:0051247 - positive regulation of protein metabolic process (P)PMID:22027397ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
acceptableOherrera,
Team That Will Beat You!!!
HUMAN:MK08GO:0051247 - positive regulation of protein metabolic process (P)PMID:22027397ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
requireschangesOherrera,
Team That Will Beat You!!!
HUMAN:MK14GO:0051247 - positive regulation of protein metabolic process (P)PMID:22027397ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableOherrera,
Team That Will Beat You!!!
HUMAN:MK14GO:0051247 - positive regulation of protein metabolic process (P)PMID:22027397ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableOherrera,
Team That Will Beat You!!!
HUMAN:KEAP1GO:0045732 - positive regulation of protein catabolic process (P)PMID:22072718ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1

0 annotations fixed by Gamertmac