MOUSE:NK1R

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Tacr1 (synonyms: Tac1r)
Protein Name(s)	Substance-P receptor SPR NK-1 receptor NK-1R Tachykinin receptor 1
External Links
UniProt	P30548
EMBL	X62934 AK038558 CH466523 BC075631 BC098332 L27828 L27826
CCDS	CCDS20262.1
PIR	S20304
RefSeq	NP_033339.2 XP_006505926.1 XP_006505927.1 XP_006505928.1
UniGene	Mm.8055
ProteinModelPortal	P30548
SMR	P30548
ChEMBL	CHEMBL2668
GuidetoPHARMACOLOGY	360
PhosphoSite	P30548
MaxQB	P30548
Ensembl	ENSMUST00000032122
GeneID	21336
KEGG	mmu:21336
UCSC	uc009clh.2
CTD	6869
MGI	MGI:98475
eggNOG	NOG331485
GeneTree	ENSGT00760000118781
HOGENOM	HOG000013018
HOVERGEN	HBG103412
InParanoid	P30548
KO	K04222
OMA	MIIVVCT
OrthoDB	EOG7N37FW
TreeFam	TF315303
Reactome	REACT_207651 REACT_252339
NextBio	300500
PRO	PR:P30548
Proteomes	UP000000589
Bgee	P30548
CleanEx	MM_TACR1
ExpressionAtlas	P30548
Genevestigator	P30548
GO	GO:0044297 GO:0071944 GO:0009986 GO:0005737 GO:0030425 GO:0016021 GO:0005886 GO:0016496 GO:0002526 GO:0002118 GO:0003051 GO:0008306 GO:0048266 GO:0042755 GO:0007616 GO:0035106 GO:0045760 GO:0045777 GO:0007204 GO:0010634 GO:0050679 GO:0046887 GO:0002687 GO:0050671 GO:0045778 GO:0035815 GO:0046878 GO:0051496 GO:0032224 GO:0032230 GO:0070474 GO:0043117 GO:0045907 GO:0014910 GO:0048660 GO:0010996 GO:0051602 GO:0032355 GO:0045471 GO:0009408 GO:0043278 GO:0035094 GO:0010193 GO:0048265 GO:0032570 GO:0060083 GO:0042713
InterPro	IPR000276 IPR017452 IPR001681 IPR000046
Pfam	PF00001
PRINTS	PR00237 PR01024 PR00244
PROSITE	PS00237 PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0070472	positive regulation of uterine smooth muscle contraction	PMID:15647454^[1]	ECO:0000314			P		from figure 1 increasing amounts of NK1 were added to the uterine preparation prior to testing. Contractile force produced by the longitudinally oriented smooth muscle fibers was recorded by a Grass FT03 force transducer connected to a MacLab data acquisition system. Uterine preparations treated with larger amounts of NK1 displayed increased levels of contraction.	complete CACAO 1965
involved_in	GO:0070472	regulation of uterine smooth muscle contraction	PMID:15647454^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1902093	positive regulation of flagellated sperm motility	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002538240 UniProtKB:P21452 UniProtKB:P25103 UniProtKB:P29371	P		Seeded From UniProt	complete
part_of	GO:0097225	sperm midpiece	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002538240 UniProtKB:P21452 UniProtKB:P25103 UniProtKB:P29371	C		Seeded From UniProt	complete
enables	GO:0016496	substance P receptor activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002930711 RGD:3811 UniProtKB:P25103	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001544873 RGD:3810 RGD:3811 UniProtKB:P21452 UniProtKB:P25103	C		Seeded From UniProt	complete
enables	GO:0004995	tachykinin receptor activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001544873 RGD:3810 RGD:3811 RGD:3812 UniProtKB:P25103 ZFIN:ZDB-GENE-061207-19 ZFIN:ZDB-GENE-090312-106	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1902093	positive regulation of flagellated sperm motility	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	P		Seeded From UniProt	complete
part_of	GO:0097225	sperm midpiece	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	C		Seeded From UniProt	complete
part_of	GO:0071944	cell periphery	PMID:12383972^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000540)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0070474	positive regulation of uterine smooth muscle contraction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
part_of	GO:0061827	sperm head	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060083	smooth muscle contraction involved in micturition	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051496	positive regulation of stress fiber assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050671	positive regulation of lymphocyte proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048660	regulation of smooth muscle cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048266	behavioral response to pain	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048265	response to pain	PMID:11805341^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046887	positive regulation of hormone secretion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046878	positive regulation of saliva secretion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045907	positive regulation of vasoconstriction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045778	positive regulation of ossification	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045777	positive regulation of blood pressure	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045760	positive regulation of action potential	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045471	response to ethanol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
part_of	GO:0044297	cell body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043117	positive regulation of vascular permeability	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042755	eating behavior	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042713	sperm ejaculation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
part_of	GO:0036126	sperm flagellum	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035815	positive regulation of renal sodium excretion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035106	operant conditioning	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035094	response to nicotine	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032230	positive regulation of synaptic transmission, GABAergic	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032224	positive regulation of synaptic transmission, cholinergic	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019233	sensory perception of pain	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
enables	GO:0016496	substance P receptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	F		Seeded From UniProt	complete
enables	GO:0016496	substance P receptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0014910	regulation of smooth muscle cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0014070	response to organic cyclic compound	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010996	response to auditory stimulus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010634	positive regulation of epithelial cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010193	response to ozone	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009725	response to hormone	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009408	response to heat	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008306	associative learning	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008217	regulation of blood pressure	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007616	long-term memory	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007611	learning or memory	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007217	tachykinin receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P25103	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0003051	angiotensin-mediated drinking behavior	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002687	positive regulation of leukocyte migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002118	aggressive behavior	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3811	P		Seeded From UniProt	complete
involved_in	GO:0070474	positive regulation of uterine smooth muscle contraction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0060083	smooth muscle contraction involved in micturition	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0051602	response to electrical stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0051496	positive regulation of stress fiber assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0050671	positive regulation of lymphocyte proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0048660	regulation of smooth muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0048266	behavioral response to pain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0046887	positive regulation of hormone secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0046878	positive regulation of saliva secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0045907	positive regulation of vasoconstriction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0045778	positive regulation of ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0045777	positive regulation of blood pressure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0045760	positive regulation of action potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0045471	response to ethanol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
part_of	GO:0044297	cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	C		Seeded From UniProt	complete
involved_in	GO:0043278	response to morphine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0043117	positive regulation of vascular permeability	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0042755	eating behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0042713	sperm ejaculation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0035815	positive regulation of renal sodium excretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0035106	operant conditioning	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0035094	response to nicotine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0032570	response to progesterone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0032355	response to estradiol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0032230	positive regulation of synaptic transmission, GABAergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0032224	positive regulation of synaptic transmission, cholinergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	C		Seeded From UniProt	complete
involved_in	GO:0019233	sensory perception of pain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
enables	GO:0016496	substance P receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	F		Seeded From UniProt	complete
involved_in	GO:0014910	regulation of smooth muscle cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0010996	response to auditory stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0010634	positive regulation of epithelial cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0010193	response to ozone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	C		Seeded From UniProt	complete
involved_in	GO:0009725	response to hormone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0009408	response to heat	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0008306	associative learning	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0008217	regulation of blood pressure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0007616	long-term memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0007611	learning or memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	C		Seeded From UniProt	complete
involved_in	GO:0003051	angiotensin-mediated drinking behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0002687	positive regulation of leukocyte migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0002526	acute inflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:0002118	aggressive behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14600 ensembl:ENSRNOP00000007984	P		Seeded From UniProt	complete
involved_in	GO:1902093	positive regulation of flagellated sperm motility	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	P		Seeded From UniProt	complete
part_of	GO:0097225	sperm midpiece	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	C		Seeded From UniProt	complete
part_of	GO:0061827	sperm head	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	C		Seeded From UniProt	complete
part_of	GO:0036126	sperm flagellum	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	C		Seeded From UniProt	complete
enables	GO:0016496	substance P receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	F		Seeded From UniProt	complete
involved_in	GO:0007217	tachykinin receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	P		Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25103 ensembl:ENSP00000303522	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F		Seeded From UniProt	complete
enables	GO:0004995	tachykinin receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000046 InterPro:IPR001681	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000046 InterPro:IPR001681	C		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000046 InterPro:IPR000276 InterPro:IPR001681	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000046 InterPro:IPR000276 InterPro:IPR001681 InterPro:IPR017452	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Patak, E et al. (2005) Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus. Biol. Reprod. 72 1125-33 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Liu, HL et al. (2002) Immunocytochemical localization of substance P receptor in hypothalamic oxytocin-containing neurons of C57 mice. Brain Res. 948 175-9 PubMed GONUTS page
↑ Jasmin, L et al. (2002) The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proc. Natl. Acad. Sci. U.S.A. 99 1029-34 PubMed GONUTS page

[PMID:15647454-1] 1.0 ^1.1 Patak, E et al. (2005) Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus. Biol. Reprod. 72 1125-33 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:12383972-3] Liu, HL et al. (2002) Immunocytochemical localization of substance P receptor in hypothalamic oxytocin-containing neurons of C57 mice. Brain Res. 948 175-9 PubMed GONUTS page

[PMID:11805341-4] Jasmin, L et al. (2002) The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proc. Natl. Acad. Sci. U.S.A. 99 1029-34 PubMed GONUTS page

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MOUSE:NK1R

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