GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:0046329 | negative regulation of JNK cascade | PMID:21196414 | IMP: Inferred from Mutant Phenotype | P | ||||
| This annotation made on page: HUMAN:M4K4 By: Taustin (group Team Subs) on 2011-11-01 20:34:06 CDT. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Vchhabria, Team KremlinOnTheCrum | 2011-11-21 15:51:00 CST | Sorry, the prior version had an extra parentheses. While it is not possible for me to access this paper, the electronic citation citing "Regulation of JNK cascade" in the same page actually suggests that M4K4 positively regulates the JNK cascade (because it colocalizes with Rap2 and only when both Rap2 and M4K4 were available in a western blot did phosphorylation of JNK2 occur, suggesting that both are necessary for activation), therefore I find something substantively wrong with this citation and think that this discrepancy must be addressed before the acceptance of this citation. Would Taustin of Team Subs please explain the data set from the paper and how it suggests a negative regulation? Otherwise I believe The following correction holds: | 0 |
| Challenge | Vchhabria, Team KremlinOnTheCrum | 2011-11-21 15:50:31 CST | While it is not possible for me to access this paper, the electronic citation citing "Regulation of JNK cascade" in the same page actually suggests that M4K4 positively regulates the JNK cascade (because it colocalizes with Rap2 and only when both Rap2 and M4K4 were available in a western blot did phosphorylation of JNK2 occur, suggesting that both are necessary for activation), therefore I find something substantively wrong with this citation and think that this discrepancy must be addressed before the acceptance of this citation. Would Taustin of Team Subs please explain the data set from the paper and how it suggests a negative regulation? Otherwise I believe The following correction holds: | 2 |
| Challenge | Gamertmac, Team She Will Be Loved | 2011-11-08 20:00:27 CST | Does not mention the cascade from the go term, and merely shows expression in various cells not a function. | 2 |
| Private Assessment | Sgouni | 2011-11-22 19:47:37 CST | You need to be an instructor to view these notes. | Unacceptable |
