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Category:Team Kitten Me Right Meow

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHUMAN:LEPAmitchell, Team Kitten Me Right Meow2014-02-11 14:42:52 CSTGO:0060612 adipose tissue development (P)PMID:24505549ECO:0000314 direct assay evidence used in manual assertion

Table 1 shows that adipose tissue increases significantly in breast cancer patients.

challenge
unacceptableHUMAN:GHRLAmitchell, Team Kitten Me Right Meow2014-02-11 12:45:45 CSTGO:0016608 growth hormone-releasing hormone activity (F)PMID:20161791ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows that Ghrelin increases the action potential of the neurons associated with the growth hormone-releasing hormone (GHRH). This shows that the increase of Ghrelin on the GHRH neurons occurs in both males and females.

challenge
unacceptableHUMAN:CDKN3Trange, Team Kitten Me Right Meow2014-02-02 18:17:48 CSTGO:0004721 phosphoprotein phosphatase activity (F)PMID:18669648ECO:0000314 direct assay evidence used in manual assertion

Figure 5 B and C are entire proteome topographical plots of up-regulated phosphorylation in G1 (B) and M-phase (C) cells. M-phase cells have much more M-phase phosphoprotein phosphatase activity than G1 protein activity seen in G1 cells based on a Protein Regulated Phosphorylation (P-RePh) scores > 10.

challenge
unacceptableRAT:Q6I9B6Trange, Team Kitten Me Right Meow2014-02-02 17:52:35 CSTGO:0005267 potassium channel activity (F)PMID:17346910ECO:0000314 direct assay evidence used in manual assertion

Figure 3 is a gel electrophoresis of the RT-PCR experiment of amplifying DNA of the rat cochlear nucleus. This gel electrophoresis shows that a subset of potassium channel's are expressed in the rat cochlear nucleus and present in all subdivisions of the cochlear nucleus.

challenge
unacceptableHUMAN:CLCN1Trange, Team Kitten Me Right Meow2014-02-02 04:11:38 CSTGO:0042493 response to drug (P)PMID:19153558ECO:0000314 direct assay evidence used in manual assertion

Figure 2Ac depicts the increase in chloride sensing of drug by increase in pH. The quick response of chloride ions to drug implies the possibility of chloride channel drug targeting for inhibition of disease progression.

challenge
unacceptableHUMAN:CLCN1Trange, Team Kitten Me Right Meow2014-02-02 03:58:10 CSTGO:0005254 chloride channel activity (F)PMID:0000037ECO:0000314 direct assay evidence used in manual assertion

Figure 1 depicts an RT-PCR of mRNAs of CLC-1 through CLC-7. Chloride ion flux is a necessary part of corneal wound electric current in human corneal epithelium. Chloride channel proteins 2,3,4, 5, and 6, but chloride channel 1 is not involved.

challenge
unacceptableHUMAN:THBGTrange, Team Kitten Me Right Meow2014-02-02 03:29:53 CSTGO:0009791 post-embryonic development (P)PMID:22260853ECO:0000314 direct assay evidence used in manual assertion

The second half of Figure 2 shows the progression of thyroxine-binding globulin over time in hypothyroid women from stimulation, to post-embryonic development. It was tested between women who were treated for hypothyroidism vs. women who were not. Overall, the increase in TBG presence is gradual over time, but the increase is not statistically significant.

challenge
updatedbyinstructorMOUSE:DNAS1Trange, Team Kitten Me Right Meow2014-02-02 02:52:14 CSTGO:0004530 deoxyribonuclease I activity (F)PMID:15015938ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1 has homogenous Dnase1 (+) and homogenous mutant Dnase1 (-) mice. Dnase1 activity was able to be detected in (+) mice in several tissues including stomach, pituitary, kidney, lymph, and thyroid. Double mutants had no Dnase1 activity in any of the tissues.

challenge
updatedbyinstructorRAT:DNAS1Trange, Team Kitten Me Right Meow2014-02-02 02:22:28 CSTGO:0004536 deoxyribonuclease activity (F)PMID:8428592ECO:0000314 direct assay evidence used in manual assertion

Fig 4.

challenge
unacceptablePIG:OXYRChong, Team Kitten Me Right Meow2014-01-30 18:03:26 CSTGO:0004990 oxytocin receptor activity (F)PMID:8393786ECO:0000314 direct assay evidence used in manual assertion

As noted by author and shown in Figure 7.

challenge
updatedbyinstructorHUMAN:SC6A4Chong, Team Kitten Me Right Meow2014-01-30 17:48:49 CSTGO:0051610 serotonin uptake (P)PMID:7681602ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 shows the antagonism of cocaine in uptake assays.

challenge
unacceptableMOUSE:5HT2BChong, Team Kitten Me Right Meow2014-01-30 17:34:04 CSTGO:0008144 drug binding (F)PMID:16940156ECO:0000314 direct assay evidence used in manual assertion

Figure 3 and Figure 6 show such activity.

challenge
updatedbyinstructorSHEEP:SNATChong, Team Kitten Me Right Meow2014-01-30 14:22:23 CSTGO:0004059 aralkylamine N-acetyltransferase activity (F)PMID:11336675ECO:0000314 direct assay evidence used in manual assertion

Figure 5

challenge
unacceptableRAT:SMSAmitchell, Team Kitten Me Right Meow2014-01-30 08:47:58 CSTGO:0005179 hormone activity (F)PMID:6120163ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows the specific nucleotides used for transcribing the gene somatostatin within the rat's DNA, so that it can later be used as a regulator of both pancreatic and gastrointestinal hormones.

challenge
requireschangesRAT:OXYRChong, Team Kitten Me Right Meow2014-01-29 23:56:25 CSTGO:0004990 oxytocin receptor activity (F)PMID:22420322ECO:0000314 direct assay evidence used in manual assertion

Figure 2. shows the binding data to support

challenge
unacceptableRAT:ITPR1Amitchell, Team Kitten Me Right Meow2014-01-29 23:35:25 CSTGO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (F)PMID:2165071ECO:0000314 direct assay evidence used in manual assertion

Figure 6 shows that the negative charged amino acid residues represent the calcium channels for which help to to moderate the inositol 1,4,5-triphosphate.

challenge
unacceptableHUMAN:PPIAAmitchell, Team Kitten Me Right Meow2014-01-29 22:08:38 CSTGO:0003755 peptidyl-prolyl cis-trans isomerase activity (F)PMID:20364129ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows that through acetylation, the Cyclophilin A can be regulated by selecting for the cis-trans peptidyl-prolyl bond.

challenge
unacceptableRAT:KAPCAAmitchell, Team Kitten Me Right Meow2014-01-28 11:42:40 CSTGO:0004691 cAMP-dependent protein kinase activity (F)PMID:11279288ECO:0000314 direct assay evidence used in manual assertion

Figure 3 clearly shows that the addition of the direct cAMP activator increases the effects on the protein kinase A as compared to the control.

challenge

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Pages in category "Team Kitten Me Right Meow"

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