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User:Amitchell

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableRAT:KAPCA2014-01-28 11:42:40 CSTGO:0004691 cAMP-dependent protein kinase activity (F)PMID:11279288ECO:0000314 direct assay evidence used in manual assertion

Figure 3 clearly shows that the addition of the direct cAMP activator increases the effects on the protein kinase A as compared to the control.

challenge
unacceptableHUMAN:PPIA2014-01-29 22:08:38 CSTGO:0003755 peptidyl-prolyl cis-trans isomerase activity (F)PMID:20364129ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows that through acetylation, the Cyclophilin A can be regulated by selecting for the cis-trans peptidyl-prolyl bond.

challenge
unacceptableRAT:ITPR12014-01-29 23:35:25 CSTGO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (F)PMID:2165071ECO:0000314 direct assay evidence used in manual assertion

Figure 6 shows that the negative charged amino acid residues represent the calcium channels for which help to to moderate the inositol 1,4,5-triphosphate.

challenge
unacceptableRAT:SMS2014-01-30 08:47:58 CSTGO:0005179 hormone activity (F)PMID:6120163ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows the specific nucleotides used for transcribing the gene somatostatin within the rat's DNA, so that it can later be used as a regulator of both pancreatic and gastrointestinal hormones.

challenge
unacceptableHUMAN:GHRL2014-02-11 12:45:45 CSTGO:0016608 growth hormone-releasing hormone activity (F)PMID:20161791ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows that Ghrelin increases the action potential of the neurons associated with the growth hormone-releasing hormone (GHRH). This shows that the increase of Ghrelin on the GHRH neurons occurs in both males and females.

challenge
unacceptableHUMAN:LEP2014-02-11 14:42:52 CSTGO:0060612 adipose tissue development (P)PMID:24505549ECO:0000314 direct assay evidence used in manual assertion

Table 1 shows that adipose tissue increases significantly in breast cancer patients.

challenge

acceptable:0
unacceptable:6
requires_changes:0
flagged:0

Annotations challenged by Amitchell

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Amitchell

What do the icons mean in the status column?

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