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SHEEP:SNAT

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Species (Taxon ID) Ovis aries (Sheep). (9940)
Gene Name(s) AANAT (synonyms: SNAT)
Protein Name(s) Serotonin N-acetyltransferase

Serotonin acetylase Aralkylamine N-acetyltransferase AA-NAT

External Links
UniProt Q29495
EMBL U29663
RefSeq NP_001009461.1
UniGene Oar.638
PDB 1B6B
1CJW
1IB1
1KUV
1KUX
1KUY
1L0C
PDBsum 1B6B
1CJW
1IB1
1KUV
1KUX
1KUY
1L0C
ProteinModelPortal Q29495
SMR Q29495
IntAct Q29495
MINT MINT-7997059
BindingDB Q29495
ChEMBL CHEMBL5452
GeneID 443531
KEGG oas:443531
CTD 15
HOVERGEN HBG016332
KO K00669
BRENDA 2.3.1.87
UniPathway UPA00837
EvolutionaryTrace Q29495
Proteomes UP000002356
GO GO:0048471
GO:0004059
GO:0071320
GO:0007623
GO:0030187
GO:0006474
Gene3D 3.40.630.30
InterPro IPR016181
IPR000182
Pfam PF00583
SUPFAM SSF55729
PROSITE PS51186

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004059

aralkylamine N-acetyltransferase activity

PMID:11336675[1]

ECO:0000314

F

Figure 5

complete
CACAO 9326

enables

GO:0004059

aralkylamine N-acetyltransferase activity

PMID:11336675[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0071320

cellular response to cAMP

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16613

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16613

C

Seeded From UniProt

complete

involved_in

GO:0030187

melatonin biosynthetic process

PMID:11313340[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007623

circadian rhythm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16613

P

Seeded From UniProt

complete

involved_in

GO:0006474

N-terminal protein amino acid acetylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16613

P

Seeded From UniProt

complete

enables

GO:0004059

aralkylamine N-acetyltransferase activity

PMID:11313340[2]

ECO:0000314

direct assay evidence used in manual assertion

F

has_direct_input:(CHEBI:50048)|has_direct_input:(CHEBI:15760)

Seeded From UniProt

complete

enables

GO:0004059

aralkylamine N-acetyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.1.87

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0030187

melatonin biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0471
UniPathway:UPA00837

P

Seeded From UniProt

complete

involved_in

GO:0048511

rhythmic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0090

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Obsil, T et al. (2001) Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation. Cell 105 257-67 PubMed GONUTS page
  2. 2.0 2.1 Coon, SL et al. (2001) cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation. J. Biol. Chem. 276 24097-107 PubMed GONUTS page