HUMAN:SC6A4

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	SLC6A4 (synonyms: HTT, SERT)
Protein Name(s)	Sodium-dependent serotonin transporter 5HT transporter 5HTT Solute carrier family 6 member 4
External Links
UniProt	P31645
EMBL	X70697 L05568 AY902473 EU099989 BC069484 U79746 AK308014
CCDS	CCDS11256.1
PIR	A47398
RefSeq	NP_001036.1
UniGene	Hs.134662 Hs.29792
ProteinModelPortal	P31645
SMR	P31645
BioGrid	112423
IntAct	P31645
MINT	MINT-577123
STRING	9606.ENSP00000261707
BindingDB	P31645
ChEMBL	CHEMBL2111346
DrugBank	DB00321 DB00543 DB00182 DB00289 DB01114 DB00215 DB01242 DB00907 DB01151 DB06700 DB01191 DB06701 DB00514 DB00988 DB01142 DB00476 DB01363 DB01175 DB00472 DB00176 DB00458 DB08918 DB00408 DB00579 DB01577 DB00422 DB06148 DB04896 DB00805 DB00370 DB01149 DB00540 DB00715 DB00454 DB00191 DB00344 DB00852 DB01104 DB01105 DB06204 DB00193 DB00656 DB00726 DB00285 DB00661 DB06684
GuidetoPHARMACOLOGY	928
TCDB	2.A.22.1.1
PhosphoSite	P31645
DMDM	400630
PaxDb	P31645
PRIDE	P31645
Ensembl	ENST00000261707 ENST00000401766
GeneID	6532
KEGG	hsa:6532
UCSC	uc002hey.5
CTD	6532
GeneCards	GC17M028521
HGNC	HGNC:11050
MIM	103780 164230 182138
neXtProt	NX_P31645
PharmGKB	PA312
eggNOG	COG0733
GeneTree	ENSGT00760000118857
HOGENOM	HOG000116406
HOVERGEN	HBG071421
InParanoid	P31645
KO	K05037
OMA	TSCKNSW
OrthoDB	EOG793B71
PhylomeDB	P31645
TreeFam	TF343812
GeneWiki	Serotonin_transporter
GenomeRNAi	6532
NextBio	25415
PRO	PR:P31645
Proteomes	UP000005640
Bgee	P31645
CleanEx	HS_HTT HS_SLC6A4
ExpressionAtlas	P31645
Genevestigator	P31645
GO	GO:0005829 GO:0012505 GO:0010008 GO:0005887 GO:0045121 GO:0043005 GO:0005886 GO:0051015 GO:0019811 GO:0008504 GO:0017137 GO:0015222 GO:0005335 GO:0048854 GO:0071321 GO:0071300 GO:0007623 GO:0007613 GO:0015844 GO:0021941 GO:0045665 GO:0046621 GO:0032227 GO:0045787 GO:0010628 GO:0051260 GO:0051259 GO:0042493 GO:0032355 GO:0001666 GO:0007584 GO:0009636 GO:0006837 GO:0051610 GO:0035176 GO:0042713 GO:0021794 GO:0042310
InterPro	IPR000175 IPR013086
PANTHER	PTHR11616
Pfam	PF03491 PF00209
PRINTS	PR01203 PR00176
PROSITE	PS00610 PS00754 PS50267

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0051610	serotonin uptake	PMID:7681602^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0048854	brain morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q60857	P	Seeded From UniProt	complete
involved_in	GO:0046621	negative regulation of organ growth	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q60857	P	Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q60857	P	Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:16870614^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:18227069^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:17506858^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:8987735^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051259	protein complex oligomerization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P31652	P	Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P31652	F	Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:16870614^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0090067	regulation of thalamus size	PMID:18378990^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0017137	Rab GTPase binding	PMID:18227069^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P20338	F	Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	PMID:18227069^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	PMID:17506858^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0009636	response to toxic substance	PMID:17575980^[7]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:16870614^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:17506858^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:18227069^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	PMID:8987735^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010414 MGI:MGI:96285 PANTHER:PTN002481010 RGD:3714 UniProtKB:P31645 WB:WBGene00003387	P	Seeded From UniProt	complete
enables	GO:0051378	serotonin binding	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002481010 UniProtKB:F1MLI6 UniProtKB:Q9XT49	F	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002481010 RGD:3714	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0035969 FB:FBgn0039915 MGI:MGI:1336891 MGI:MGI:1336892 MGI:MGI:95627 MGI:MGI:95760 PANTHER:PTN000177662 RGD:3714 RGD:3715 RGD:620533 RGD:621822 UniProtKB:P31645 UniProtKB:Q01959 UniProtKB:Q9Y345	C	Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010414 PANTHER:PTN002481010 RGD:3714 UniProtKB:P31645 WB:WBGene00003387	F	Seeded From UniProt	complete
involved_in	GO:0015844	monoamine transport	PMID:16024787^[9]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0008504	monoamine transmembrane transporter activity	PMID:16024787^[9]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0015293	P	Seeded From UniProt	complete
involved_in	GO:0006837	serotonin transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	C	Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	F	Seeded From UniProt	complete
involved_in	GO:0001666	response to hypoxia	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
part_of	GO:0099154	serotonergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	C	Seeded From UniProt	complete
part_of	GO:0099056	integral component of presynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	C	Seeded From UniProt	complete
part_of	GO:0099055	integral component of postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	C	Seeded From UniProt	complete
involved_in	GO:0071321	cellular response to cGMP	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0071300	cellular response to retinoic acid	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0051259	protein complex oligomerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	F	Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	C	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	F	Seeded From UniProt	complete
involved_in	GO:0042713	sperm ejaculation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0042310	vasoconstriction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0032355	response to estradiol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0032227	negative regulation of synaptic transmission, dopaminergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
enables	GO:0019811	cocaine binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	F	Seeded From UniProt	complete
enables	GO:0017075	syntaxin-1 binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	F	Seeded From UniProt	complete
enables	GO:0017022	myosin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	F	Seeded From UniProt	complete
involved_in	GO:0014064	positive regulation of serotonin secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	C	Seeded From UniProt	complete
involved_in	GO:0010033	response to organic substance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0007613	memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0007584	response to nutrient	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0007420	brain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31652 ensembl:ENSRNOP00000004717	P	Seeded From UniProt	complete
involved_in	GO:0071310	cellular response to organic substance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
enables	GO:0050998	nitric-oxide synthase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	F	Seeded From UniProt	complete
involved_in	GO:0048854	brain morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
involved_in	GO:0046621	negative regulation of organ growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
involved_in	GO:0045787	positive regulation of cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
	GO:0051610	serotonin uptake	PMID:7681602^[1]	ECO:0000315			P	Figure 2 shows the antagonism of cocaine in uptake assays.	complete CACAO 9340
involved_in	GO:0035176	social behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
involved_in	GO:0006837	serotonin transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P	Seeded From UniProt	complete
enables	GO:0005328	neurotransmitter:sodium symporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037272	F	Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013086	F	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013086	C	Seeded From UniProt	complete
involved_in	GO:0006836	neurotransmitter transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013086	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000175	C	Seeded From UniProt	complete
involved_in	GO:0042136	neurotransmitter biosynthetic process	Reactome:R-HSA-112311	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-444008	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	Reactome:R-HSA-444008	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
involved_in	GO:0006836	neurotransmitter transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0532	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
enables	GO:0015293	symporter activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0769	F	Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0100	C	Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0147	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Ramamoorthy, S et al. (1993) Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Proc. Natl. Acad. Sci. U.S.A. 90 2542-6 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Müller, HK et al. (2006) Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2. J. Biol. Chem. 281 28901-9 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Ahmed, BA et al. (2008) Serotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporter. J. Biol. Chem. 283 9388-98 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Brenner, B et al. (2007) Plasma serotonin levels and the platelet serotonin transporter. J. Neurochem. 102 206-15 PubMed GONUTS page
↑ ^5.0 ^5.1 Qian, Y et al. (1997) Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. J. Neurosci. 17 45-57 PubMed GONUTS page
↑ Young, KA et al. (2008) Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume. Br J Psychiatry 192 285-9 PubMed GONUTS page
↑ Flach, CF et al. (2007) Differential expression of intestinal membrane transporters in cholera patients. FEBS Lett. 581 3183-8 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^9.0 ^9.1 Jiang, W et al. (2005) IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity. Mol. Cell. Biol. 25 6496-508 PubMed GONUTS page

[PMID:7681602-1] 1.0 ^1.1 Ramamoorthy, S et al. (1993) Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Proc. Natl. Acad. Sci. U.S.A. 90 2542-6 PubMed GONUTS page

[PMID:16870614-2] 2.0 ^2.1 ^2.2 Müller, HK et al. (2006) Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2. J. Biol. Chem. 281 28901-9 PubMed GONUTS page

[PMID:18227069-3] 3.0 ^3.1 ^3.2 ^3.3 Ahmed, BA et al. (2008) Serotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporter. J. Biol. Chem. 283 9388-98 PubMed GONUTS page

[PMID:17506858-4] 4.0 ^4.1 ^4.2 Brenner, B et al. (2007) Plasma serotonin levels and the platelet serotonin transporter. J. Neurochem. 102 206-15 PubMed GONUTS page

[PMID:8987735-5] 5.0 ^5.1 Qian, Y et al. (1997) Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. J. Neurosci. 17 45-57 PubMed GONUTS page

[PMID:18378990-6] Young, KA et al. (2008) Major depression, 5HTTLPR genotype, suicide and antidepressant influences on thalamic volume. Br J Psychiatry 192 285-9 PubMed GONUTS page

[PMID:17575980-7] Flach, CF et al. (2007) Differential expression of intestinal membrane transporters in cholera patients. FEBS Lett. 581 3183-8 PubMed GONUTS page

[PMID:21873635-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:16024787-9] 9.0 ^9.1 Jiang, W et al. (2005) IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity. Mol. Cell. Biol. 25 6496-508 PubMed GONUTS page

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HUMAN:SC6A4

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