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User:Wtrimble

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHUMAN:PTPRU2014-01-31 17:46:11 CSTGO:0016791 phosphatase activity (F)PMID:24260274ECO:0000314 direct assay evidence used in manual assertion

Figure 4: PTPRU genes in astrocytes were identified as key genes affecting HSV-1 replication.

challenge
unacceptableMOUSE:MERTK2014-01-31 18:12:58 CSTGO:0002834 regulation of response to tumor cell (P)PMID:23867499ECO:0000316 genetic interaction evidence used in manual assertion

Figure 1

Mice with MerTK–/– microenvironment experienced decreased tumor malignancy.

challenge
updatedbyinstructorHUMAN:DNLI42014-01-31 18:25:39 CSTGO:0003910 DNA ligase (ATP) activity (F)PMID:22192310ECO:0000314 direct assay evidence used in manual assertion

Fig. 4.

challenge
updatedbyinstructorHUMAN:DNLI32014-01-31 18:42:11 CSTGO:0090298 negative regulation of mitochondrial DNA replication (P)PMID:21878356ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 1 B,C. DNA ligase III levels in cell lysates prepared from cells treated with scramble (Sc) dsRNA or DNA ligase III-specific (LIII) dsRNA.

challenge
unacceptableHUMAN:DNLI42014-02-02 00:26:09 CSTGO:0003909 DNA ligase activity (F)PMID:23523427ECO:0000314 direct assay evidence used in manual assertion

The SDS-PAGE gel of fractions eluted from a heparin column and from a Superdex column led to protein bands forming next to the same molecular weight markers.

challenge

acceptable:0
unacceptable:3
requires_changes:0
flagged:0

Annotations challenged by Wtrimble

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableSirons,
Team Takin This Outside
HUMAN:TAUGO:0007015 - actin filament organization (P)GO_REF:0000019ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
unacceptableAstephens2,
Team Bacon Pancakes
HUMAN:FADDPMID:7538907ECO:0000247 sequence alignment evidence used in manual assertionchallengeC: 4
updatedbyinstructorKdiawara,
Team Lobster Soul
HUMAN:HS90BGO:0097435 - supramolecular fiber organization (P)PMID:24466266ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 8
updatedbyinstructorMalexander2,
Team Pancakes At Nite
HUMAN:BTKGO:0018108 - peptidyl-tyrosine phosphorylation (P)PMID:11606584ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1

0 annotations fixed by Wtrimble

What do the icons mean in the status column?

assessment icons.jpg