MOUSE:MERTK

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Mertk (synonyms: Mer)
Protein Name(s)	Tyrosine-protein kinase Mer Proto-oncogene c-Mer Receptor tyrosine kinase MerTK
External Links
UniProt	Q60805
EMBL	U21301 L11625
CCDS	CCDS16716.1
PIR	I49276
RefSeq	NP_032613.1
UniGene	Mm.239655
ProteinModelPortal	Q60805
SMR	Q60805
IntAct	Q60805
STRING	10090.ENSMUSP00000014505
MEROPS	I43.001
PhosphoSite	Q60805
MaxQB	Q60805
PaxDb	Q60805
PRIDE	Q60805
DNASU	17289
Ensembl	ENSMUST00000014505
GeneID	17289
KEGG	mmu:17289
UCSC	uc008mgt.1
CTD	10461
MGI	MGI:96965
eggNOG	COG0515
GeneTree	ENSGT00770000120499
HOGENOM	HOG000231685
HOVERGEN	HBG006346
InParanoid	Q60805
KO	K05117
OMA	NEIGWSA
OrthoDB	EOG77DJ5C
PhylomeDB	Q60805
TreeFam	TF317402
BRENDA	2.7.10.1
Reactome	REACT_225233
NextBio	291808
PRO	PR:Q60805
Proteomes	UP000000589
Bgee	Q60805
CleanEx	MM_MERTK
ExpressionAtlas	Q60805
Genevestigator	Q60805
GO	GO:0005737 GO:0005615 GO:0016021 GO:0001750 GO:0016028 GO:0005524 GO:0004714 GO:0043277 GO:0001779 GO:0051250 GO:0030168 GO:0050766 GO:0043491 GO:0060041 GO:0032940 GO:0007283 GO:0034446 GO:0060068
Gene3D	2.60.40.10
InterPro	IPR003961 IPR007110 IPR013783 IPR003599 IPR011009 IPR000719 IPR017441 IPR001245 IPR008266 IPR020635
Pfam	PF00041 PF07714
PRINTS	PR00109
SMART	SM00060 SM00409 SM00219
SUPFAM	SSF49265 SSF56112
PROSITE	PS50853 PS50835 PS00107 PS50011 PS00109

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
Contributes to	GO:0002834	regulation of response to tumor cell	PMID:23867499^[1]	ECO:0000316			P		Figure 1 Mice with MerTK–/– microenvironment experienced decreased tumor malignancy.	Missing: with/from CACAO 9372
involved_in	GO:0043277	apoptotic cell clearance	PMID:18159085^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0043235	receptor complex	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015380 FB:FBgn0024245 FB:FBgn0033791 PANTHER:PTN002356460 UniProtKB:A6QR62 UniProtKB:O15146 UniProtKB:P00533 UniProtKB:P04626 UniProtKB:P04629 UniProtKB:P06213 UniProtKB:P07949 UniProtKB:P08069 UniProtKB:P11362 UniProtKB:P14616 UniProtKB:P17948 UniProtKB:P21860 UniProtKB:P35916 UniProtKB:Q01973 UniProtKB:Q08345 UniProtKB:Q15303 UniProtKB:Q16288 UniProtKB:Q16620	C		Seeded From UniProt	complete
enables	GO:0017147	Wnt-protein binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015380 FB:FBgn0033791 MGI:MGI:101766 PANTHER:PTN002521290	F		Seeded From UniProt	complete
involved_in	GO:0016477	cell migration	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1347244 MGI:MGI:96969 PANTHER:PTN002814495 RGD:3082 ZFIN:ZDB-GENE-041014-1	P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101766 PANTHER:PTN002521290	P		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1347244 MGI:MGI:96969 PANTHER:PTN002814495 RGD:3082 WB:WBGene00020504 ZFIN:ZDB-GENE-041014-1	P		Seeded From UniProt	complete
involved_in	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003366 FB:FBgn0003731 FB:FBgn0003733 FB:FBgn0283499 MGI:MGI:104757 MGI:MGI:109378 MGI:MGI:1096337 MGI:MGI:1339758 MGI:MGI:1345277 MGI:MGI:95276 MGI:MGI:95278 MGI:MGI:95294 MGI:MGI:95522 MGI:MGI:95523 MGI:MGI:95524 MGI:MGI:95525 MGI:MGI:95558 MGI:MGI:95561 MGI:MGI:96575 MGI:MGI:96677 MGI:MGI:96683 MGI:MGI:96969 MGI:MGI:97384 MGI:MGI:97530 MGI:MGI:97531 MGI:MGI:97902 MGI:MGI:98277 MGI:MGI:99216 MGI:MGI:99611 MGI:MGI:99612 MGI:MGI:99654 PANTHER:PTN002356460 RGD:2543 RGD:2611 RGD:2612 RGD:2621 RGD:2869 RGD:2917 RGD:2965 RGD:3082 RGD:3213 RGD:3214 RGD:3284 RGD:3285 RGD:620144 RGD:620714 RGD:620831 RGD:621737 RGD:69323 UniProtKB:A6QR62 UniProtKB:P00533 UniProtKB:P04626 UniProtKB:P04629 UniProtKB:P06213 UniProtKB:P07949 UniProtKB:P08069 UniProtKB:P09619 UniProtKB:P10721 UniProtKB:P11362 UniProtKB:P16234 UniProtKB:P17948 UniProtKB:P21709 UniProtKB:P21802 UniProtKB:P22455 UniProtKB:P22607 UniProtKB:P29317 UniProtKB:P29320 UniProtKB:P35916 UniProtKB:P35968 UniProtKB:P54753 UniProtKB:P54760 UniProtKB:P54762 UniProtKB:P54764 UniProtKB:Q02763 UniProtKB:Q08345 UniProtKB:Q15303 UniProtKB:Q15375 UniProtKB:Q16288 UniProtKB:Q16620 UniProtKB:Q16832 UniProtKB:Q5JZY3 UniProtKB:Q91987 WB:WBGene00001184 WB:WBGene00006868 ZFIN:ZDB-GENE-020503-1 ZFIN:ZDB-GENE-020503-2 ZFIN:ZDB-GENE-060503-14 ZFIN:ZDB-GENE-070713-2 ZFIN:ZDB-GENE-980526-255 ZFIN:ZDB-GENE-980526-326 ZFIN:ZDB-GENE-990415-62	P		Seeded From UniProt	complete
involved_in	GO:0006909	phagocytosis	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1347244 PANTHER:PTN001231011 RGD:69283 UniProtKB:P30530 UniProtKB:Q12866	P		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003366 FB:FBgn0003731 FB:FBgn0003733 FB:FBgn0011829 FB:FBgn0015380 FB:FBgn0032006 FB:FBgn0283499 MGI:MGI:103581 MGI:MGI:104771 MGI:MGI:109378 MGI:MGI:98277 MGI:MGI:99611 PANTHER:PTN002356460 RGD:1560587 RGD:3213 RGD:3214 RGD:70957 UniProtKB:P04629 UniProtKB:P06213 UniProtKB:P07949 UniProtKB:P16234 UniProtKB:P17948 UniProtKB:P21709 UniProtKB:P21802 UniProtKB:P22455 UniProtKB:P22607 UniProtKB:P29317 UniProtKB:P29320 UniProtKB:P35968 UniProtKB:P54753 UniProtKB:P54760 UniProtKB:P54762 UniProtKB:Q02763 UniProtKB:Q16620 UniProtKB:Q9UM73 WB:WBGene00000289 WB:WBGene00000898	C		Seeded From UniProt	complete
enables	GO:0004714	transmembrane receptor protein tyrosine kinase activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0003733 FB:FBgn0040505 FB:FBgn0283499 MGI:MGI:109378 MGI:MGI:1339758 MGI:MGI:1345277 MGI:MGI:95276 MGI:MGI:95294 MGI:MGI:95522 MGI:MGI:95524 MGI:MGI:95558 MGI:MGI:95561 MGI:MGI:96677 MGI:MGI:96683 MGI:MGI:96969 MGI:MGI:97384 MGI:MGI:97530 MGI:MGI:97902 MGI:MGI:98277 MGI:MGI:99611 MGI:MGI:99612 MGI:MGI:99654 PANTHER:PTN002356460 RGD:2543 RGD:2611 RGD:2621 RGD:2869 RGD:2917 RGD:2965 RGD:3082 RGD:3213 RGD:3214 RGD:3284 RGD:3285 RGD:620144 RGD:620714 RGD:620831 RGD:621737 UniProtKB:P00533 UniProtKB:P04626 UniProtKB:P04629 UniProtKB:P06213 UniProtKB:P07333 UniProtKB:P07949 UniProtKB:P08069 UniProtKB:P09619 UniProtKB:P10721 UniProtKB:P11362 UniProtKB:P14616 UniProtKB:P16234 UniProtKB:P17948 UniProtKB:P21709 UniProtKB:P21802 UniProtKB:P22455 UniProtKB:P22607 UniProtKB:P29317 UniProtKB:P29320 UniProtKB:P35916 UniProtKB:P35968 UniProtKB:P54753 UniProtKB:P54760 UniProtKB:P54762 UniProtKB:Q08345 UniProtKB:Q15303 UniProtKB:Q16620 UniProtKB:Q16832 UniProtKB:Q5JZY3 UniProtKB:Q91987 UniProtKB:Q9UM73 WB:WBGene00000289 WB:WBGene00006868 WB:WBGene00020504 ZFIN:ZDB-GENE-980526-255	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000107	negative regulation of leukocyte apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q12866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0097350	neutrophil clearance	PMID:23878224^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1347244	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060068	vagina development	PMID:18393392^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:104294 MGI:MGI:1347244	P	results_in_development_of:(EMAPA:18986)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060041	retina development in camera-type eye	PMID:21052544^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	results_in_development_of:(EMAPA:17168)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051250	negative regulation of lymphocyte activation	PMID:11452127^[7]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:104294 MGI:MGI:1347244	P	regulates_o_occurs_in:(CL:0000542)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050766	positive regulation of phagocytosis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q12866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043491	protein kinase B signaling	PMID:15650770^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95660	P	occurs_in:(CL:0000233)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043277	apoptotic cell clearance	PMID:23878224^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1347244	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043277	apoptotic cell clearance	PMID:18159085^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:104294 MGI:MGI:1347244	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043277	apoptotic cell clearance	PMID:17442946^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2387768	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034446	substrate adhesion-dependent cell spreading	PMID:15650770^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2387765	P	occurs_in:(CL:0000233)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032940	secretion by cell	PMID:15650770^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2387765	P	occurs_in:(CL:0000233)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030168	platelet activation	PMID:15650770^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2387765	P		Seeded From UniProt	complete
part_of	GO:0016028	rhabdomere	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q12866	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007283	spermatogenesis	PMID:10227296^[10]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:104294 MGI:MGI:1347244	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006909	phagocytosis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q12866	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006909	phagocytosis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69283	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006468	protein phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69283	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q12866	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q12866	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001818	negative regulation of cytokine production	PMID:23878224^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1347244	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001779	natural killer cell differentiation	PMID:16751775^[11]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:104294 MGI:MGI:1347244	P	results_in_acquisition_of_features_of:(CL:0000623)	Seeded From UniProt	complete
part_of	GO:0001750	photoreceptor outer segment	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:69283	C		Seeded From UniProt	complete
involved_in	GO:0018108	peptidyl-tyrosine phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004713	P		Seeded From UniProt	complete
involved_in	GO:0018108	peptidyl-tyrosine phosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004714	P		Seeded From UniProt	complete
involved_in	GO:0018108	peptidyl-tyrosine phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004713	P		Seeded From UniProt	complete
involved_in	GO:0018108	peptidyl-tyrosine phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004714	P		Seeded From UniProt	complete
involved_in	GO:0006909	phagocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P57097 ensembl:ENSRNOP00000023419	P		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P57097 ensembl:ENSRNOP00000023419	P		Seeded From UniProt	complete
part_of	GO:0001750	photoreceptor outer segment	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P57097 ensembl:ENSRNOP00000023419	C		Seeded From UniProt	complete
involved_in	GO:2000107	negative regulation of leukocyte apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q12866 ensembl:ENSP00000295408	P		Seeded From UniProt	complete
involved_in	GO:0050766	positive regulation of phagocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q12866 ensembl:ENSP00000295408	P		Seeded From UniProt	complete
part_of	GO:0016028	rhabdomere	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q12866 ensembl:ENSP00000295408	C		Seeded From UniProt	complete
involved_in	GO:0006909	phagocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q12866 ensembl:ENSP00000295408	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q12866 ensembl:ENSP00000295408	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q12866 ensembl:ENSP00000295408	C		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266	F		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020635	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245 InterPro:IPR008266 InterPro:IPR020635	P		Seeded From UniProt	complete
enables	GO:0004714	transmembrane receptor protein tyrosine kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.10.1	F		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0004713	protein tyrosine kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0829	F		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Cook, RS et al. (2013) MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis. J. Clin. Invest. 123 3231-42 PubMed GONUTS page
↑ ^2.0 ^2.1 Xiong, W et al. (2008) Gas6 and the Tyro 3 receptor tyrosine kinase subfamily regulate the phagocytic function of Sertoli cells. Reproduction 135 77-87 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Bosurgi, L et al. (2013) Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer. Proc. Natl. Acad. Sci. U.S.A. 110 13091-6 PubMed GONUTS page
↑ Wu, H et al. (2008) High incidence of distal vaginal atresia in mice lacking Tyro3 RTK subfamily. Mol. Reprod. Dev. 75 1775-82 PubMed GONUTS page
↑ Won, J et al. (2011) Mouse model resources for vision research. J Ophthalmol 2011 391384 PubMed GONUTS page
↑ Lu, Q & Lemke, G (2001) Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 293 306-11 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 Angelillo-Scherrer, A et al. (2005) Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. J. Clin. Invest. 115 237-46 PubMed GONUTS page
↑ Seitz, HM et al. (2007) Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells. J. Immunol. 178 5635-42 PubMed GONUTS page
↑ Lu, Q et al. (1999) Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. Nature 398 723-8 PubMed GONUTS page
↑ Caraux, A et al. (2006) Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases. Nat. Immunol. 7 747-54 PubMed GONUTS page

[PMID:23867499-1] Cook, RS et al. (2013) MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis. J. Clin. Invest. 123 3231-42 PubMed GONUTS page

[PMID:18159085-2] 2.0 ^2.1 Xiong, W et al. (2008) Gas6 and the Tyro 3 receptor tyrosine kinase subfamily regulate the phagocytic function of Sertoli cells. Reproduction 135 77-87 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:23878224-4] 4.0 ^4.1 ^4.2 Bosurgi, L et al. (2013) Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer. Proc. Natl. Acad. Sci. U.S.A. 110 13091-6 PubMed GONUTS page

[PMID:18393392-5] Wu, H et al. (2008) High incidence of distal vaginal atresia in mice lacking Tyro3 RTK subfamily. Mol. Reprod. Dev. 75 1775-82 PubMed GONUTS page

[PMID:21052544-6] Won, J et al. (2011) Mouse model resources for vision research. J Ophthalmol 2011 391384 PubMed GONUTS page

[PMID:11452127-7] Lu, Q & Lemke, G (2001) Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 293 306-11 PubMed GONUTS page

[PMID:15650770-8] 8.0 ^8.1 ^8.2 ^8.3 Angelillo-Scherrer, A et al. (2005) Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. J. Clin. Invest. 115 237-46 PubMed GONUTS page

[PMID:17442946-9] Seitz, HM et al. (2007) Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells. J. Immunol. 178 5635-42 PubMed GONUTS page

[PMID:10227296-10] Lu, Q et al. (1999) Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. Nature 398 723-8 PubMed GONUTS page

[PMID:16751775-11] Caraux, A et al. (2006) Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases. Nat. Immunol. 7 747-54 PubMed GONUTS page

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MOUSE:MERTK

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