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Category:GO:0043491 ! phosphatidylinositol 3-kinase/protein kinase B signal transduction
name: phosphatidylinositol 3-kinase/protein kinase B signal transduction
namespace: biological_process
def: "An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway." [PMID:20517722, PMID:22952397]
synonym: "AKT signal transduction" RELATED []
synonym: "AKT signaling" RELATED []
synonym: "AKT signaling cascade" RELATED []
synonym: "AKT signalling cascade" RELATED []
synonym: "phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction" EXACT []
synonym: "PI3K-PKB/Akt pathway" EXACT []
synonym: "PI3K/Akt signal transduction" EXACT []
synonym: "PI3K/PKB signal transduction" EXACT []
synonym: "PKB signal transduction" RELATED []
synonym: "PKB signaling" RELATED []
synonym: "PKB signaling cascade" RELATED []
synonym: "PKB signalling cascade" RELATED []
synonym: "protein kinase B signal transduction" RELATED []
synonym: "protein kinase B signaling" RELATED []
synonym: "protein kinase B signaling cascade" RELATED []
synonym: "protein kinase B signalling cascade" RELATED []
is_a: GO:0141124 ! intracellular signaling cassette
AmiGO
<GOterm>GO:0043491</GOterm>
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This category has the following 2 subcategories, out of 2 total.
Pages in category "GO:0043491 ! phosphatidylinositol 3-kinase/protein kinase B signal transduction"
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