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User:Relledge

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableMOUSE:TNR162014-01-30 11:47:25 CSTGO:0009986 cell surface (C)PMID:3815101ECO:0000314 direct assay evidence used in manual assertion

Figure 1A. Western blotting reveals the presence of p75NTR on cell surfaces.

challenge
unacceptableMOUSE:NTRK12014-01-30 11:57:44 CSTGO:0009986 cell surface (C)PMID:3815101ECO:0000314 direct assay evidence used in manual assertion

Figure 1A. Western blotting displays that NTRK1 (TrkA) was present on cell surfaces.

challenge
unacceptableMOUSE:TNR162014-01-30 12:21:25 CSTGO:0045773 positive regulation of axon extension (P)PMID:3815101ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2b. APP deficient neurons lead to decreased cell surface levels of p75NTR, and Figure 3A. shows that the decreased cell surface levels of p75NTR in APP deficient cells significantly decrease neurite outgrowth relative to control cells.

challenge
unacceptablePIG:PEPA2014-02-01 11:21:47 CSTGO:0051603 proteolysis involved in cellular protein catabolic process (P)PMID:2195218ECO:0000314 direct assay evidence used in manual assertion

Figure 1. Increased rate of addition of pepsin to pepsinogen solution demonstrated increased rate of reduction of the amount of pepsinogen in solution.

challenge
unacceptablePIG:PEPA2014-02-01 12:29:16 CSTGO:0008233 peptidase activity (F)PMID:2195218ECO:0000314 direct assay evidence used in manual assertion

Figure 1. Pepsinogen levels reduce at increased rates when increased levels of pepsin are added to the solution.

challenge

acceptable:0
unacceptable:5
requires_changes:0
flagged:0

Annotations challenged by Relledge

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableGrolfe,
Team Pancakes At Nite
HUMAN:CIB1GO:0008427 - calcium-dependent protein kinase inhibitor activity (F)PMID:20473878ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
unacceptableGrolfe,
Team Pancakes At Nite
HUMAN:CIB1GO:0005515 - protein binding (F)PMID:20473878ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
updatedbyinstructorBmanieri,
Team Chicken Day
HUMAN:COGA1GO:0033622 - integrin activation (P)PMID:16754661ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
updatedbyinstructorAross,
Team BAMF
DROME:ABLGO:0010592 - positive regulation of lamellipodium assembly (P)PMID:24466097ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4

0 annotations fixed by Relledge

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