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This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

It is now the 4th OPEN Period for CACAO Phage Hunters 2018! It will end on Sunday April 22, 2018 at 11:59 pm CDT
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

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DROME:ABL

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Abl (synonyms: ABL-1, Dash)
Protein Name(s) Tyrosine-protein kinase Abl

D-ash Protein abelson

External Links
UniProt P00522
EMBL M19692
M19690
M19691
AE014296
AY058497
K01042
PIR A28128
RefSeq NP_001287085.1
NP_524843.2
UniGene Dm.5397
ProteinModelPortal P00522
SMR P00522
BioGrid 69904
IntAct P00522
PaxDb P00522
EnsemblMetazoa FBtr0075357
GeneID 45821
KEGG dme:Dmel_CG4032
CTD 45821
FlyBase FBgn0000017
eggNOG COG0515
GeneTree ENSGT00760000118938
InParanoid P00522
KO K06619
OrthoDB EOG7GTT2V
BRENDA 2.7.10.2
Reactome REACT_180258
REACT_181315
REACT_246045
REACT_256055
SignaLink P00522
GenomeRNAi 45821
NextBio 838372
PRO PR:P00522
Proteomes UP000000803
Bgee P00522
ExpressionAtlas P00522
GO GO:0005912
GO:0045179
GO:0030424
GO:0005938
GO:0005911
GO:0005737
GO:0005829
GO:0019897
GO:0005927
GO:0005524
GO:0004715
GO:0004713
GO:0007411
GO:0016199
GO:0007409
GO:0007417
GO:0048749
GO:0007303
GO:0007391
GO:0003382
GO:0002009
GO:0008045
GO:0045886
GO:0001764
GO:0018108
GO:0072499
GO:0003402
GO:0046827
GO:0006468
GO:0008064
GO:0008360
GO:0032880
GO:0031647
GO:0007419
GO:0007370
Gene3D 3.30.505.10
InterPro IPR015015
IPR011009
IPR000719
IPR017441
IPR001245
IPR000980
IPR001452
IPR008266
IPR020635
Pfam PF08919
PF07714
PF00017
PF00018
PRINTS PR00401
PR00452
PR00109
SMART SM00808
SM00252
SM00326
SM00219
SUPFAM SSF50044
SSF55550
SSF56112
PROSITE PS00107
PS50011
PS00109
PS50001
PS50002

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0007611

learning or memory

PMID:1321066[1]

IMP: Inferred from Mutant Phenotype

P

figure 2, flies with mutant latheo gene have poor memory, statistically significant.

complete
CACAO 3437

GO:0007268

synaptic transmission

PMID:10402193[2]

IMP: Inferred from Mutant Phenotype

P

fig 3 synaptuc transmission is elevated in lat mutants

complete
CACAO 3442

GO:0004713

protein tyrosine kinase activity

PMID:2832740[3]

ISA: Inferred from Sequence Alignment

UniProtKB:P00519


F

tyrosine kinase activity inferred from sequence similarity to human abl tyrosine kinase. kinase activity observed from expression products of transformed e.coli with Drosophila abl

complete
CACAO 3402

GO:0021785

branchiomotor neuron axon guidance

PMID:10069335[4]

IMP: Inferred from Mutant Phenotype

P

See Figure 4C for mutant phenotype of abl expression.

complete
CACAO 5080

GO:0010592

positive regulation of lamellipodium assembly

PMID:24466097[5]

IMP: Inferred from Mutant Phenotype

P

Compared to WT control, Abl neurons exhibited tendency to show fewer veil-like structures and well developed, large lamellipodia (>4 µm2) occurred only at a lower frequency (Fig. 5)

complete
CACAO 9390

GO:0010977

negative regulation of neuron projection development

PMID:24466097[5]

IMP: Inferred from Mutant Phenotype

P

Consistent with the altered neuronal growth in the larval CNS culture [24], neurons in Abl cultures displayed... more swollen, dark nodes along neurites (Fig. 4B1).

complete
CACAO 9391

GO:0000166

nucleotide binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0001764

neuron migration

PMID:21726548[6]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0002009

morphogenesis of an epithelium

PMID:12147138[7]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

complete

GO:0003382

epithelial cell morphogenesis

PMID:11756472[8]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0003402

planar cell polarity pathway involved in axis elongation

PMID:22340496[9]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0829

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

PMID:10892742[10]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

PMID:10908587[11]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

PMID:17804420[12]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

PMID:19217428[13]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

PMID:2832740[3]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

PMID:2832740[3]

ISA: Inferred from Sequence Alignment

UniProtKB:P00519

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

PMID:2832740[3]

ISS: Inferred from Sequence or Structural Similarity

F

Seeded From UniProt

Missing: with/from

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015015

F

Seeded From UniProt

complete

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.10.2

F

Seeded From UniProt

complete

GO:0004715

non-membrane spanning protein tyrosine kinase activity

PMID:2175256[14]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0005102

receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:10069336[15]

IPI: Inferred from Physical Interaction

UniProtKB:P16621

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:10220404[16]

IPI: Inferred from Physical Interaction

UniProtKB:Q8T4F7

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:10498863[17]

IPI: Inferred from Physical Interaction

FB:FBgn0020510

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:16054027[18]

IPI: Inferred from Physical Interaction

FB:FBgn0085443

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:7535279[19]

IPI: Inferred from Physical Interaction

UniProtKB:Q8T4F7

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR015015
InterPro:IPR017441

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:1295746[20]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005829

cytosol

PMID:17804420[12]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005829

cytosol

PMID:25294944[21]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005829

cytosol

Reactome:REACT_19143

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0005829

cytosol

Reactome:REACT_19250

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0005911

cell-cell junction

PMID:1295746[20]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005912

adherens junction

PMID:12147138[7]

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0005927

muscle tendon junction

PMID:1295746[20]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005938

cell cortex

PMID:16054027[18]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266
InterPro:IPR015015
InterPro:IPR020635

P

Seeded From UniProt

complete

GO:0006468

protein phosphorylation

PMID:10908587[11]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

complete

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0007268

synaptic transmission

PMID:10402193[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007303

cytoplasmic transport, nurse cell to oocyte

PMID:19576200[22]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007370

ventral furrow formation

PMID:17202187[23]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007391

dorsal closure

PMID:11756472[8]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007391

dorsal closure

PMID:12147138[7]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

complete

GO:0007409

axonogenesis

PMID:2175256[14]

IGI: Inferred from Genetic Interaction

FB:FBgn0004108

P

Seeded From UniProt

complete

GO:0007411

axon guidance

PMID:10798396[24]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007411

axon guidance

PMID:10892742[10]

IGI: Inferred from Genetic Interaction

FB:FBgn0005631

P

Seeded From UniProt

complete

GO:0007411

axon guidance

PMID:10892742[10]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007411

axon guidance

PMID:12781136[25]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007411

axon guidance

PMID:19217428[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007411

axon guidance

PMID:20498300[26]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007411

axon guidance

PMID:2406026[27]

IGI: Inferred from Genetic Interaction

FB:FBgn0262742

P

Seeded From UniProt

complete

GO:0007417

central nervous system development

PMID:2502313[28]

IGI: Inferred from Genetic Interaction

FB:FBgn0004108

P

Seeded From UniProt

complete

GO:0007419

ventral cord development

PMID:19211897[29]

IGI: Inferred from Genetic Interaction

FB:FBgn0033159

P

Seeded From UniProt

complete

GO:0007419

ventral cord development

PMID:19217428[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007611

learning or memory

PMID:1321066[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008045

motor neuron axon guidance

PMID:17568577[30]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008064

regulation of actin polymerization or depolymerization

PMID:12231351[31]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0008360

regulation of cell shape

PMID:12147138[7]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

complete

GO:0008360

regulation of cell shape

PMID:14527345[32]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008360

regulation of cell shape

PMID:17202187[23]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0010592

positive regulation of lamellipodium assembly

PMID:24466097[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0010977

negative regulation of neuron projection development

PMID:24466097[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016199

axon midline choice point recognition

PMID:12973825[33]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016301

kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

GO:0016310

phosphorylation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

GO:0016740

transferase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

GO:0018108

peptidyl-tyrosine phosphorylation

PMID:17804420[12]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0018108

peptidyl-tyrosine phosphorylation

PMID:19217428[13]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0019897

extrinsic component of plasma membrane

PMID:1295746[20]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0021785

branchiomotor neuron axon guidance

PMID:10069335[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030154

cell differentiation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0030424

axon

PMID:2175256[14]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

C

Seeded From UniProt

complete

GO:0031647

regulation of protein stability

PMID:17804420[12]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0032880

regulation of protein localization

PMID:17804420[12]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0038083

peptidyl-tyrosine autophosphorylation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0042127

regulation of cell proliferation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0042981

regulation of apoptotic process

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN001562982

P

Seeded From UniProt

complete

GO:0045087

innate immune response

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0045179

apical cortex

PMID:17202187[23]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0045886

negative regulation of synaptic growth at neuromuscular junction

PMID:19675132[34]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0046827

positive regulation of protein export from nucleus

PMID:19217428[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0048749

compound eye development

PMID:19217428[13]

IGI: Inferred from Genetic Interaction

FB:FBgn0000320

P

Seeded From UniProt

complete

GO:0048813

dendrite morphogenesis

PMID:16003769[35]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0072499

photoreceptor cell axon guidance

PMID:19217428[13]

IGI: Inferred from Genetic Interaction

FB:FBgn0000320

P

Seeded From UniProt

complete

GO:0072499

photoreceptor cell axon guidance

PMID:19217428[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

colocalizes_with

GO:0070938

contractile ring

PMID:25294944[21]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Boynton, S & Tully, T (1992) latheo, a new gene involved in associative learning and memory in Drosophila melanogaster, identified from P element mutagenesis. Genetics 131 655-72 PubMed GONUTS page
  2. 2.0 2.1 Rohrbough, J et al. (1999) latheo, a Drosophila gene involved in learning, regulates functional synaptic plasticity. Neuron 23 55-70 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Henkemeyer, MJ et al. (1988) DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog. Mol. Cell. Biol. 8 843-53 PubMed GONUTS page
  4. 4.0 4.1 Wills, Z et al. (1999) Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo. Neuron 22 291-9 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Liu, L & Wu, CF (2014) Distinct effects of Abelson kinase mutations on myocytes and neurons in dissociated Drosophila embryonic cultures: mimicking of high temperature. PLoS ONE 9 e86438 PubMed GONUTS page
  6. Zhu, Z & Bhat, KM (2011) The Hem protein mediates neuronal migration by inhibiting WAVE degradation and functions opposite of Abelson tyrosine kinase. Dev. Biol. 357 283-94 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 Harden, N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70 181-203 PubMed GONUTS page
  8. 8.0 8.1 Grevengoed, EE et al. (2001) Abelson kinase regulates epithelial morphogenesis in Drosophila. J. Cell Biol. 155 1185-98 PubMed GONUTS page
  9. Tamada, M et al. (2012) Abl regulates planar polarized junctional dynamics through β-catenin tyrosine phosphorylation. Dev. Cell 22 309-19 PubMed GONUTS page
  10. 10.0 10.1 10.2 Bashaw, GJ et al. (2000) Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor. Cell 101 703-15 PubMed GONUTS page
  11. 11.0 11.1 Morrison, DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J. Cell Biol. 150 F57-62 PubMed GONUTS page
  12. 12.0 12.1 12.2 12.3 12.4 Huang, CH et al. (2007) The involvement of Abl and PTP61F in the regulation of Abi protein localization and stability and lamella formation in Drosophila S2 cells. J. Biol. Chem. 282 32442-52 PubMed GONUTS page
  13. 13.0 13.1 13.2 13.3 13.4 13.5 13.6 13.7 Xiong, W et al. (2009) Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm. Dev. Cell 16 271-9 PubMed GONUTS page
  14. 14.0 14.1 14.2 Henkemeyer, M et al. (1990) A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization. Cell 63 949-60 PubMed GONUTS page
  15. Wills, Z et al. (1999) The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance. Neuron 22 301-12 PubMed GONUTS page
  16. Ahern-Djamali, SM et al. (1999) Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled. Proc. Natl. Acad. Sci. U.S.A. 96 4977-82 PubMed GONUTS page
  17. Juang, JL & Hoffmann, FM (1999) Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity. Oncogene 18 5138-47 PubMed GONUTS page
  18. 18.0 18.1 Jékely, G et al. (2005) Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration. Dev. Cell 9 197-207 PubMed GONUTS page
  19. Gertler, FB et al. (1995) enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties. Genes Dev. 9 521-33 PubMed GONUTS page
  20. 20.0 20.1 20.2 20.3 Bennett, RL & Hoffmann, FM (1992) Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions. Development 116 953-66 PubMed GONUTS page
  21. 21.0 21.1 Lye, CM et al. (2014) Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos. Development 141 4006-17 PubMed GONUTS page
  22. Gates, J et al. (2009) Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesis. Dev. Biol. 333 90-107 PubMed GONUTS page
  23. 23.0 23.1 23.2 Fox, DT & Peifer, M (2007) Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila. Development 134 567-78 PubMed GONUTS page
  24. Liebl, EC et al. (2000) Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding. Neuron 26 107-18 PubMed GONUTS page
  25. Crowner, D et al. (2003) Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway. Curr. Biol. 13 967-72 PubMed GONUTS page
  26. Lowery, LA et al. (2010) Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila. Genetics 185 1311-25 PubMed GONUTS page
  27. Elkins, T et al. (1990) Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations. Cell 60 565-75 PubMed GONUTS page
  28. Gertler, FB et al. (1989) Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabled. Cell 58 103-13 PubMed GONUTS page
  29. Yu, HH et al. (2009) Endodomain diversity in the Drosophila Dscam and its roles in neuronal morphogenesis. J. Neurosci. 29 1904-14 PubMed GONUTS page
  30. Dorsten, JN et al. (2007) Frazzled regulation of myosin II activity in the Drosophila embryonic CNS. Dev. Biol. 308 120-32 PubMed GONUTS page
  31. Martin, P & Wood, W (2002) Epithelial fusions in the embryo. Curr. Opin. Cell Biol. 14 569-74 PubMed GONUTS page
  32. Kiger, AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J. Biol. 2 27 PubMed GONUTS page
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