PIG:PEPA

Species (Taxon ID)	Sus scrofa (Pig). (9823)
Gene Name(s)	PGA
Protein Name(s)	Pepsin A
External Links
UniProt	P00791
EMBL	M20920 J04601
PIR	JT0307
UniGene	Ssc.219
PDB	1F34 1PSA 1YX9 2PSG 3PEP 3PSG 4PEP 5PEP
PDBsum	1F34 1PSA 1YX9 2PSG 3PEP 3PSG 4PEP 5PEP
ProteinModelPortal	P00791
SMR	P00791
MINT	MINT-142105
STRING	9823.ENSSSCP00000013926
BindingDB	P00791
ChEMBL	CHEMBL2714
Allergome	2924
MEROPS	A01.001
PRIDE	P00791
Ensembl	ENSSSCT00000014312
eggNOG	NOG248684
GeneTree	ENSGT00760000118929
HOGENOM	HOG000197681
HOVERGEN	HBG000482
InParanoid	P00791
OMA	FQGMNIP
OrthoDB	EOG7HQN88
TreeFam	TF314990
EvolutionaryTrace	P00791
Proteomes	UP000008227
GO	GO:0005576 GO:0004190 GO:0007586
Gene3D	2.40.70.10
InterPro	IPR001461 IPR001969 IPR012848 IPR021109
PANTHER	PTHR13683
Pfam	PF07966 PF00026
PRINTS	PR00792
SUPFAM	SSF50630
PROSITE	PS00141

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0051603	proteolysis involved in cellular protein catabolic process	PMID:2195218	ECO:0000314			P		Figure 1. Increased rate of addition of pepsin to pepsinogen solution demonstrated increased rate of reduction of the amount of pepsinogen in solution.	complete CACAO 9387
	GO:0008233	peptidase activity	PMID:2195218	ECO:0000314			F		Figure 1. Pepsinogen levels reduce at increased rates when increased levels of pepsin are added to the solution.	complete CACAO 9388
involved_in	GO:0030163	protein catabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000201569 PANTHER:PTN000342793 UniProtKB:P0CY27 UniProtKB:Q5A8N2 UniProtKB:Q5AC08	P		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000190503 CGD:CAL0000194661 CGD:CAL0000196689 CGD:CAL0000201140 MGI:MGI:1346542 PANTHER:PTN000342793 RGD:621511 SGD:S000002551 TAIR:locus:2008940 UniProtKB:P00797 UniProtKB:P0CY27 UniProtKB:P41748 UniProtKB:P43094 UniProtKB:P56817 UniProtKB:Q59VH7 UniProtKB:Q5AC08 UniProtKB:Q8I6Z5 WB:WBGene00000217	P		Seeded From UniProt	complete
enables	GO:0004190	aspartic-type endopeptidase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	CGD:CAL0000196689 MGI:MGI:107361 MGI:MGI:1915935 MGI:MGI:88562 PANTHER:PTN000342793 PomBase:SPCC1795.09 RGD:2446 SGD:S000001277 SGD:S000002551 SGD:S000004110 SGD:S000004111 TAIR:locus:2145954 UniProtKB:P00797 UniProtKB:P0CY27 UniProtKB:P14091 UniProtKB:P20142 UniProtKB:P56817 UniProtKB:Q4WNV0 UniProtKB:Q5AC08 UniProtKB:Q8I6Z5 UniProtKB:Q9LTW4 UniProtKB:Q9Y5Z0	F		Seeded From UniProt	complete
enables	GO:0004190	aspartic-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001461 InterPro:IPR001969 InterPro:IPR012848	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001461 InterPro:IPR001969 InterPro:IPR012848	P		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
involved_in	GO:0007586	digestion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0222	P		Seeded From UniProt	complete
enables	GO:0004190	aspartic-type endopeptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0064	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
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References

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