MOUSE:TNR16

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Ngfr (synonyms: Tnfrsf16)
Protein Name(s)	Tumor necrosis factor receptor superfamily member 16 Low affinity neurotrophin receptor p75NTR Low-affinity nerve growth factor receptor NGF receptor
External Links
UniProt	Q9Z0W1
EMBL	AF105292
UniGene	Mm.283893
ProteinModelPortal	Q9Z0W1
SMR	Q9Z0W1
IntAct	Q9Z0W1
MINT	MINT-243918
PhosphoSite	Q9Z0W1
MaxQB	Q9Z0W1
PaxDb	Q9Z0W1
PRIDE	Q9Z0W1
MGI	MGI:97323
eggNOG	NOG39106
HOVERGEN	HBG060431
InParanoid	Q9Z0W1
Reactome	REACT_202271 REACT_209641
PRO	PR:Q9Z0W1
Proteomes	UP000000589
Genevestigator	Q9Z0W1
GO	GO:0009986 GO:0005737 GO:0016021 GO:0097481 GO:0005886 GO:0005035 GO:0048406 GO:0017137 GO:0006915 GO:0007411 GO:0007417 GO:0032922 GO:0007623 GO:0016048 GO:0042593 GO:0031069 GO:0006886 GO:0040037 GO:0051799 GO:0021675 GO:2001235 GO:0048146 GO:0042488 GO:0010468 GO:2001273 GO:0043588
Gene3D	1.10.533.10
InterPro	IPR011029 IPR000488 IPR001368 IPR022325
Pfam	PF00531 PF00020
PRINTS	PR01966
SMART	SM00005 SM00208
SUPFAM	SSF47986
PROSITE	PS50017 PS00652 PS50050

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009986	cell surface	PMID:3815101^[1]	ECO:0000314			C		Figure 1A. Western blotting reveals the presence of p75NTR on cell surfaces.	complete CACAO 9323
	GO:0045773	positive regulation of axon extension	PMID:3815101^[1]	ECO:0000315			P		Figure 2b. APP deficient neurons lead to decreased cell surface levels of p75NTR, and Figure 3A. shows that the decreased cell surface levels of p75NTR in APP deficient cells significantly decrease neurite outgrowth relative to control cells.	complete CACAO 9325
enables	GO:0005516	calmodulin binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P08138	F		Seeded From UniProt	complete
involved_in	GO:0035907	dorsal aorta development	PMID:11559852^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P18519	C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:10021336^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0001678	cellular glucose homeostasis	PMID:22460790^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042593	glucose homeostasis	PMID:22460790^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032922	circadian regulation of gene expression	PMID:23785138^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0017137	Rab GTPase binding	PMID:22460790^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	PMID:23785138^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006886	intracellular protein transport	PMID:22460790^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0048406	nerve growth factor binding	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 RGD:3177 UniProtKB:P18519	F		Seeded From UniProt	complete
enables	GO:0015026	coreceptor activity	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001133900 UniProtKB:P08138	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 RGD:3177	C		Seeded From UniProt	complete
involved_in	GO:0007266	Rho protein signal transduction	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001133900 UniProtKB:P08138	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 RGD:3177 UniProtKB:P08138 UniProtKB:P18519	C		Seeded From UniProt	complete
enables	GO:0005035	death receptor activity	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97323 PANTHER:PTN001133900 UniProtKB:P08138	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2001235	positive regulation of apoptotic signaling pathway	PMID:10764727^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000463	positive regulation of excitatory postsynaptic potential	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000377	regulation of reactive oxygen species metabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000179	positive regulation of neural precursor cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904646	cellular response to amyloid-beta	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1901216	positive regulation of neuron death	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1900182	positive regulation of protein localization to nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	P		Seeded From UniProt	complete
enables	GO:0070678	preprotein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0061000	negative regulation of dendritic spine development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051968	positive regulation of synaptic transmission, glutamatergic	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051902	negative regulation of mitochondrial depolarization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051897	positive regulation of protein kinase B signaling	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051799	negative regulation of hair follicle development	PMID:10588868^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P	regulates_o_results_in_development_of:(EMAPA:18771) regulates_o_has_participant:(CL:0000057)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051402	neuron apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	P		Seeded From UniProt	complete
enables	GO:0048406	nerve growth factor binding	PMID:1317267^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0048406	nerve growth factor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048146	positive regulation of fibroblast proliferation	PMID:10588868^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
part_of	GO:0045334	clathrin-coated endocytic vesicle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043588	skin development	PMID:1317267^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P	results_in_development_of:(EMAPA:32726)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043524	negative regulation of neuron apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043410	positive regulation of MAPK cascade	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
enables	GO:0043121	neurotrophin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043066	negative regulation of apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043065	positive regulation of apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042488	positive regulation of odontogenesis of dentin-containing tooth	PMID:9268129^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P	regulates_o_results_in_formation_of:(EMAPA:32897)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	PMID:10588868^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P	regulates_o_occurs_in:(EMAPA:18771) regulates_o_occurs_in:(CL:0000057)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035025	positive regulation of Rho protein signal transduction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034599	cellular response to oxidative stress	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
part_of	GO:0032809	neuronal cell body membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0032590	dendrite membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032224	positive regulation of synaptic transmission, cholinergic	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031643	positive regulation of myelination	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031069	hair follicle morphogenesis	PMID:10588868^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P		Seeded From UniProt	complete
part_of	GO:0030135	coated vesicle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021675	nerve development	PMID:1317267^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019233	sensory perception of pain	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016525	negative regulation of angiogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016048	detection of temperature stimulus	PMID:1317267^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P	occurs_in:(EMAPA:32726)	Seeded From UniProt	complete
enables	GO:0015026	coreceptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	F		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:24069373^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010977	negative regulation of neuron projection development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010976	positive regulation of neuron projection development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010941	regulation of cell death	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010468	regulation of gene expression	PMID:10588868^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P	occurs_in:(EMAPA:18771) occurs_in:(CL:0000057) has_regulation_target:(MGI:MGI:95523)	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009611	response to wounding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007417	central nervous system development	PMID:11978834^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007411	axon guidance	PMID:11978834^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1857226	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007266	Rho protein signal transduction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007165	signal transduction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	P		Seeded From UniProt	complete
part_of	GO:0005911	cell-cell junction	PMID:21300049^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:10536054^[14]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16255)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0005791	rough endoplasmic reticulum	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:25433207^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:19295126^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0005635	nuclear envelope	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	C		Seeded From UniProt	complete
enables	GO:0005516	calmodulin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	F		Seeded From UniProt	complete
enables	GO:0005168	neurotrophin TRKA receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
enables	GO:0005035	death receptor activity	PMID:10764727^[7]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005035	death receptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08138	F		Seeded From UniProt	complete
enables	GO:0001540	amyloid-beta binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3177	F		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000488	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-MMU-205099 Reactome:R-MMU-205060 Reactome:R-MMU-204967 Reactome:R-MMU-194544	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0053	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Fung, SJ et al. (1987) Differential labeling of the vestibular complex following unilateral injections of horseradish peroxidase into the cat and rat locus coeruleus. Brain Res. 401 347-52 PubMed GONUTS page
↑ von Schack, D et al. (2001) Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system. Nat. Neurosci. 4 977-8 PubMed GONUTS page
↑ Wu, JJ et al. (1999) Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors. Development 126 1161-73 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Baeza-Raja, B et al. (2012) p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proc. Natl. Acad. Sci. U.S.A. 109 5838-43 PubMed GONUTS page
↑ ^5.0 ^5.1 Baeza-Raja, B et al. (2013) p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. J. Neurosci. 33 10221-34 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^7.0 ^7.1 Mukai, J et al. (2000) NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR. J. Biol. Chem. 275 17566-70 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 Botchkareva, NV et al. (1999) A role for p75 neurotrophin receptor in the control of hair follicle morphogenesis. Dev. Biol. 216 135-53 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 Lee, KF et al. (1992) Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69 737-49 PubMed GONUTS page
↑ Sarram, S et al. (1997) Dental innervation and CGRP in adult p75-deficient mice. J. Comp. Neurol. 385 297-308 PubMed GONUTS page
↑ Breiderhoff, T et al. (2013) Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. PLoS ONE 8 e75006 PubMed GONUTS page
↑ ^12.0 ^12.1 McQuillen, PS et al. (2002) A novel role for p75NTR in subplate growth cone complexity and visual thalamocortical innervation. J. Neurosci. 22 3580-93 PubMed GONUTS page
↑ Tateya, T et al. (2011) Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development. Dev. Biol. 352 329-40 PubMed GONUTS page
↑ Young, HM et al. (1999) Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut. Dev. Dyn. 216 137-52 PubMed GONUTS page
↑ Serinagaoglu, Y et al. (2015) Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development. Dev. Biol. 398 97-109 PubMed GONUTS page
↑ Malin, D et al. (2009) The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration. J. Cell. Sci. 122 995-1004 PubMed GONUTS page

[PMID:3815101-1] 1.0 ^1.1 Fung, SJ et al. (1987) Differential labeling of the vestibular complex following unilateral injections of horseradish peroxidase into the cat and rat locus coeruleus. Brain Res. 401 347-52 PubMed GONUTS page

[PMID:11559852-2] von Schack, D et al. (2001) Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system. Nat. Neurosci. 4 977-8 PubMed GONUTS page

[PMID:10021336-3] Wu, JJ et al. (1999) Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors. Development 126 1161-73 PubMed GONUTS page

[PMID:22460790-4] 4.0 ^4.1 ^4.2 ^4.3 Baeza-Raja, B et al. (2012) p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proc. Natl. Acad. Sci. U.S.A. 109 5838-43 PubMed GONUTS page

[PMID:23785138-5] 5.0 ^5.1 Baeza-Raja, B et al. (2013) p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. J. Neurosci. 33 10221-34 PubMed GONUTS page

[PMID:21873635-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10764727-7] 7.0 ^7.1 Mukai, J et al. (2000) NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR. J. Biol. Chem. 275 17566-70 PubMed GONUTS page

[PMID:10588868-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 Botchkareva, NV et al. (1999) A role for p75 neurotrophin receptor in the control of hair follicle morphogenesis. Dev. Biol. 216 135-53 PubMed GONUTS page

[PMID:1317267-9] 9.0 ^9.1 ^9.2 ^9.3 Lee, KF et al. (1992) Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69 737-49 PubMed GONUTS page

[PMID:9268129-10] Sarram, S et al. (1997) Dental innervation and CGRP in adult p75-deficient mice. J. Comp. Neurol. 385 297-308 PubMed GONUTS page

[PMID:24069373-11] Breiderhoff, T et al. (2013) Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. PLoS ONE 8 e75006 PubMed GONUTS page

[PMID:11978834-12] 12.0 ^12.1 McQuillen, PS et al. (2002) A novel role for p75NTR in subplate growth cone complexity and visual thalamocortical innervation. J. Neurosci. 22 3580-93 PubMed GONUTS page

[PMID:21300049-13] Tateya, T et al. (2011) Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development. Dev. Biol. 352 329-40 PubMed GONUTS page

[PMID:10536054-14] Young, HM et al. (1999) Expression of Ret-, p75(NTR)-, Phox2a-, Phox2b-, and tyrosine hydroxylase-immunoreactivity by undifferentiated neural crest-derived cells and different classes of enteric neurons in the embryonic mouse gut. Dev. Dyn. 216 137-52 PubMed GONUTS page

[PMID:25433207-15] Serinagaoglu, Y et al. (2015) Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development. Dev. Biol. 398 97-109 PubMed GONUTS page

[PMID:19295126-16] Malin, D et al. (2009) The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration. J. Cell. Sci. 122 995-1004 PubMed GONUTS page

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