My Annotations
Status | Page | Date/Time | GO Term (Aspect) | Reference | Evidence | Notes | Links |
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updatedbyinstructor | STRMU:Q8DWM3 | 2013-04-11 10:04:59 CDT | GO:0044011 single-species biofilm formation on inanimate substrate (P) | PMID:21078847 | ECO:0000315 mutant phenotype evidence used in manual assertion | Fig. 4A/4B shows that biofilm formation on glass surfaces was impaired in GbpB knockdown mutants.
| challenge |
acceptable | STRMU:NAGB | 2013-04-11 10:59:49 CDT | GO:0006040 amino sugar metabolic process (P) | PMID:22438919 | ECO:0000314 direct assay evidence used in manual assertion | Figure 2 shows the addition of N-acetylglucosamine (GlcNAc)increases the expression of NagB but decreases the expression of GlmS, a gene which functionally opposes that of NagB. GlmS is known to be a key factor affecting the entrance of amino sugars into glycolysis and cell wall synthesis in several other bacteria, however their roles in S. mutans remain unclear. This paper, and specifically figure 2, confirms this function in S. mutans as well.
| challenge |
updatedbyinstructor | KLEP3:APBE1 | 2013-04-14 11:47:10 CDT | GO:0017013 protein flavinylation (P) | PMID:23558683 | ECO:0000314 direct assay evidence used in manual assertion | | challenge |
acceptable:1
unacceptable:0
requires_changes:0
flagged:0
Annotations challenged by Drumhel2
Status | Author,Group | Page | GO Term (Aspect) | Reference | Evidence | Links | Page history |
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updatedbyinstructor | Emeller, Team The Z-team | DANRE:B0R0V8 | GO:0061075 - positive regulation of neural retina development (P) | PMID:18836173 | ECO:0000315 mutant phenotype evidence used in manual assertion | challenge | C: 4
fixed by Harigjen |
unacceptable | Alana.Cheplowitz, Team Gene Hackman | STRCH:Q934F8 | GO:0043581 - obsolete mycelium development (P) | PMID:22309453 | ECO:0000316 genetic interaction evidence used in manual assertion | challenge | C: 3
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updatedbyinstructor | Vthompsonui, Team Buster McThunderstick | MOUSE:SMAD4 | GO:0042733 - embryonic digit morphogenesis (P) | PMID:23034633 | ECO:0000315 mutant phenotype evidence used in manual assertion | challenge | C: 2
fixed by Drumhel2 |
unacceptable | Elkington, Team Old Worm | CAEEL:Q9GZG4 | GO:1900369 - negative regulation of post-transcriptional gene silencing by regulatory ncRNA (Figure 4A) | PMID:17110334 | IMP: Inferred from Mutant Phenotype | challenge | C: 3
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updatedbyinstructor | Sadie.jones, Team Amino Acid | STRCO:FTSZ | GO:0000935 - division septum (C) | PMID:19156202 | ECO:0000314 direct assay evidence used in manual assertion | challenge | C: 1
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updatedbyinstructor | Neillmeg, Team Peacock | HUMAN:DCR1A | GO:0035312 - 5'-3' DNA exonuclease activity (F) | PMID:22692201 | ECO:0000314 direct assay evidence used in manual assertion | challenge | C: 3
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updatedbyinstructor | Mill2034, Team Its Miller Time | ARATH:AB1D | GO:0016042 - lipid catabolic process (P) | PMID:12065405 | ECO:0000315 mutant phenotype evidence used in manual assertion | challenge | C: 4
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updatedbyinstructor | Pallasbr, Team KEGGstands at PubMed | HUMAN:E2F1 | GO:0045893 - positive regulation of DNA-templated transcription (P) | PMID:22476863 | ECO:0000314 direct assay evidence used in manual assertion | challenge | C: 3
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updatedbyinstructor | Ratiujer, Team Gene Simmons 2013 | 9BACL:I0BWH5 | GO:0044406 - adhesion of symbiont to host (P) | PMID:22615573 | ECO:0000315 mutant phenotype evidence used in manual assertion | challenge | C: 3
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1 annotations fixed by Drumhel2
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