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User:Drumhel2

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorSTRMU:Q8DWM32013-04-11 10:04:59 CDTGO:0044011 single-species biofilm formation on inanimate substrate (P)PMID:21078847ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 4A/4B shows that biofilm formation on glass surfaces was impaired in GbpB knockdown mutants.

challenge
acceptableSTRMU:NAGB2013-04-11 10:59:49 CDTGO:0006040 amino sugar metabolic process (P)PMID:22438919ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows the addition of N-acetylglucosamine (GlcNAc)increases the expression of NagB but decreases the expression of GlmS, a gene which functionally opposes that of NagB. GlmS is known to be a key factor affecting the entrance of amino sugars into glycolysis and cell wall synthesis in several other bacteria, however their roles in S. mutans remain unclear. This paper, and specifically figure 2, confirms this function in S. mutans as well.

challenge
updatedbyinstructorKLEP3:APBE12013-04-14 11:47:10 CDTGO:0017013 protein flavinylation (P)PMID:23558683ECO:0000314 direct assay evidence used in manual assertion

Figure 7.

challenge

acceptable:1
unacceptable:0
requires_changes:0
flagged:0

Annotations challenged by Drumhel2

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
updatedbyinstructorEmeller,
Team The Z-team
DANRE:B0R0V8GO:0061075 - positive regulation of neural retina development (P)PMID:18836173ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4

fixed by Harigjen
unacceptableAlana.Cheplowitz,
Team Gene Hackman
STRCH:Q934F8GO:0043581 - obsolete mycelium development (P)PMID:22309453ECO:0000316 genetic interaction evidence used in manual assertionchallengeC: 3
updatedbyinstructorVthompsonui,
Team Buster McThunderstick
MOUSE:SMAD4GO:0042733 - embryonic digit morphogenesis (P)PMID:23034633ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2

fixed by Drumhel2
unacceptableElkington,
Team Old Worm
CAEEL:Q9GZG4GO:1900369 - negative regulation of post-transcriptional gene silencing by RNA (Figure 4A)PMID:17110334IMP: Inferred from Mutant Phenotype challengeC: 3
updatedbyinstructorSadie.jones,
Team Amino Acid
STRCO:FTSZGO:0000935 - division septum (C)PMID:19156202ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1
updatedbyinstructorNeillmeg,
Team Peacock
HUMAN:DCR1AGO:0035312 - 5'-3' exodeoxyribonuclease activity (F)PMID:22692201ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
updatedbyinstructorMill2034,
Team Its Miller Time
ARATH:AB1DGO:0016042 - lipid catabolic process (P)PMID:12065405ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4
updatedbyinstructorPallasbr,
Team KEGGstands at PubMed
HUMAN:E2F1GO:0045893 - positive regulation of DNA-templated transcription (P)PMID:22476863ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
updatedbyinstructorRatiujer,
Team Gene Simmons 2013
9BACL:I0BWH5GO:0044406 - adhesion of symbiont to host (P)PMID:22615573ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3

1 annotations fixed by Drumhel2

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