Category:Team Peacock

Figure 1 shows that a mutation in the p53 results in mutations in the DNA-binding domain, in DLBCL (Diffuse large B-cell lymphoma) patients

Figure 2 shows that a mutation of the p53 results in poor survival rates for those with DLBCL

Figure 3

see figures 1 and 2 to see how the protein is the one to help with chromosome segregation

see figure 2 for the results of the direct assay and the proof that the protein produces cytokine that is involved in inflammatory responce

see figure 2 to experimental results that show the proteins ablity to deacetylase activity

see Figure 2 in paper to see the experiment done to show that the protein is used to regulate the S phase of mitotic cell cycle

Figure 1 shows the experiment to show the exonuclease activity

Figure 1A indicates that a loss of CHD1 results in defective polytene chromosomes. Figure 3 shows that a lack in CHD1 can led to increased levels of HP1a and the H3K9me2 repressive chromatin. Fig 4 shows that an increase in CHD1 leads to disruption in chromosome structure, whereas a decrease of the ATP inactivated form of CHD1 didn't have much affect.

GO term changed per Ticket-3833 ~~~~

Figure 4 shows how the mutation of this gene affects the regulation of the WFS1 protien

Figure 3 and the paragraph explaining the results of the essay explain how the protein has N-methyltransferase activity.