User:Raoneha

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	DROME:CHD1	2013-03-28 14:03:56 CDT	GO:0140658 ATP-dependent chromatin remodeler activity (F)	PMID:23533627	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1A indicates that a loss of CHD1 results in defective polytene chromosomes. Figure 3 shows that a lack in CHD1 can led to increased levels of HP1a and the H3K9me2 repressive chromatin. Fig 4 shows that an increase in CHD1 leads to disruption in chromosome structure, whereas a decrease of the ATP inactivated form of CHD1 didn't have much affect. GO term changed per Ticket-3833 ~~~~	challenge
unacceptable	HUMAN:P53	2013-04-14 15:33:11 CDT	GO:0030330 DNA damage response, signal transduction by p53 class mediator (P)	PMID:22955915	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1 shows that a mutation in the p53 results in mutations in the DNA-binding domain, in DLBCL (Diffuse large B-cell lymphoma) patients Figure 2 shows that a mutation of the p53 results in poor survival rates for those with DLBCL	challenge

acceptable:1
unacceptable:1
requires_changes:0
flagged:0

Annotations challenged by Raoneha

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
requireschanges	Dylan.browning, Team Phatty Acidz	MOUSE:CLN8	GO:0045184 - establishment of protein localization (P)	PMID:23142642	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 3
updatedbyinstructor	Sara.oravec, Team Endoplasmic Reticulum	MOUSE:TMOD1	GO:0070307 - lens fiber cell development (P)	PMID:23144950	ECO:0000316 genetic interaction evidence used in manual assertion	challenge	C: 7
requireschanges	Fitzg128, Team The Schmosbies	BACSU:FLGM	GO:0043064 - obsolete flagellum organization (P)	PMID:22730131	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1

0 annotations fixed by Raoneha

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