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HUMAN:DCR1A

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) DCLRE1A (synonyms: KIAA0086, SNM1, SNM1A)
Protein Name(s) DNA cross-link repair 1A protein

SNM1 homolog A hSNM1 hSNM1A

External Links
UniProt Q6PJP8
EMBL D42045
AY607842
AL592546
CH471066
CH471066
BC013124
BC062582
CCDS CCDS7584.1
RefSeq NP_001258745.1
NP_055696.3
XP_006718153.1
UniGene Hs.1560
Hs.703616
PDB 4B87
PDBsum 4B87
ProteinModelPortal Q6PJP8
SMR Q6PJP8
BioGrid 115263
STRING 9606.ENSP00000355185
PhosphoSite Q6PJP8
DMDM 311033461
MaxQB Q6PJP8
PaxDb Q6PJP8
PRIDE Q6PJP8
Ensembl ENST00000361384
ENST00000369305
GeneID 9937
KEGG hsa:9937
UCSC uc001law.3
CTD 9937
GeneCards GC10M115584
HGNC HGNC:17660
HPA HPA036907
MIM 609682
neXtProt NX_Q6PJP8
PharmGKB PA27174
eggNOG COG1236
GeneTree ENSGT00530000063183
HOGENOM HOG000168450
HOVERGEN HBG081418
InParanoid Q6PJP8
KO K15340
OMA PDGLLCT
OrthoDB EOG71VSSC
PhylomeDB Q6PJP8
TreeFam TF314510
ChiTaRS DCLRE1A
GeneWiki DCLRE1A
GenomeRNAi 9937
NextBio 37488
PRO PR:Q6PJP8
Proteomes UP000005640
Bgee Q6PJP8
CleanEx HS_DCLRE1A
Genevestigator Q6PJP8
GO GO:0005634
GO:0007067
GO:0006289
Gene3D 3.60.15.10
InterPro IPR001279
IPR011084
Pfam PF07522
SMART SM00849
SUPFAM SSF56281

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0035312

5'-3' exodeoxyribonuclease activity

PMID:22692201[1]

ECO:0000314

F

Figure 3

complete
CACAO 7542

enables

GO:0035312

5'-3' exodeoxyribonuclease activity

PMID:22692201[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0036297

interstrand cross-link repair

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000581728
PomBase:SPAC22A12.01c
SGD:S000004745
UniProtKB:Q9H816

P

Seeded From UniProt

complete

enables

GO:0035312

5'-3' exodeoxyribonuclease activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000581728
UniProtKB:Q6PJP8

F

Seeded From UniProt

complete

involved_in

GO:0031848

protection from non-homologous end joining at telomere

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2156057
PANTHER:PTN000581728
UniProtKB:Q9H816

P

Seeded From UniProt

complete

involved_in

GO:0006303

double-strand break repair via nonhomologous end joining

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000581728
dictyBase:DDB_G0277755

P

Seeded From UniProt

complete

enables

GO:0003684

damaged DNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000581728
SGD:S000004745

F

Seeded From UniProt

complete

part_of

GO:0000784

nuclear chromosome, telomeric region

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000581728
UniProtKB:Q9H816

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001650

fibrillar center

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0035312

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0035312

P

Seeded From UniProt

complete

involved_in

GO:0036297

interstrand cross-link repair

Reactome:R-HSA-6783310

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-6785986
Reactome:R-HSA-6785732

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0132

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Sengerová, B et al. (2012) Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases. J. Biol. Chem. 287 26254-67 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page