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HUMAN:DCR1A
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | DCLRE1A (synonyms: KIAA0086, SNM1, SNM1A) | |
Protein Name(s) | DNA cross-link repair 1A protein
SNM1 homolog A hSNM1 hSNM1A | |
External Links | ||
UniProt | Q6PJP8 | |
EMBL | D42045 AY607842 AL592546 CH471066 CH471066 BC013124 BC062582 | |
CCDS | CCDS7584.1 | |
RefSeq | NP_001258745.1 NP_055696.3 XP_006718153.1 | |
UniGene | Hs.1560 Hs.703616 | |
PDB | 4B87 | |
PDBsum | 4B87 | |
ProteinModelPortal | Q6PJP8 | |
SMR | Q6PJP8 | |
BioGrid | 115263 | |
STRING | 9606.ENSP00000355185 | |
PhosphoSite | Q6PJP8 | |
DMDM | 311033461 | |
MaxQB | Q6PJP8 | |
PaxDb | Q6PJP8 | |
PRIDE | Q6PJP8 | |
Ensembl | ENST00000361384 ENST00000369305 | |
GeneID | 9937 | |
KEGG | hsa:9937 | |
UCSC | uc001law.3 | |
CTD | 9937 | |
GeneCards | GC10M115584 | |
HGNC | HGNC:17660 | |
HPA | HPA036907 | |
MIM | 609682 | |
neXtProt | NX_Q6PJP8 | |
PharmGKB | PA27174 | |
eggNOG | COG1236 | |
GeneTree | ENSGT00530000063183 | |
HOGENOM | HOG000168450 | |
HOVERGEN | HBG081418 | |
InParanoid | Q6PJP8 | |
KO | K15340 | |
OMA | PDGLLCT | |
OrthoDB | EOG71VSSC | |
PhylomeDB | Q6PJP8 | |
TreeFam | TF314510 | |
ChiTaRS | DCLRE1A | |
GeneWiki | DCLRE1A | |
GenomeRNAi | 9937 | |
NextBio | 37488 | |
PRO | PR:Q6PJP8 | |
Proteomes | UP000005640 | |
Bgee | Q6PJP8 | |
CleanEx | HS_DCLRE1A | |
Genevestigator | Q6PJP8 | |
GO | GO:0005634 GO:0007067 GO:0006289 | |
Gene3D | 3.60.15.10 | |
InterPro | IPR001279 IPR011084 | |
Pfam | PF07522 | |
SMART | SM00849 | |
SUPFAM | SSF56281 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0035312 |
5'-3' exodeoxyribonuclease activity |
ECO:0000314 |
F |
Figure 3 |
complete | |||||
enables |
GO:0035312 |
5'-3' exodeoxyribonuclease activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0036297 |
interstrand cross-link repair |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000581728 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0035312 |
5'-3' exodeoxyribonuclease activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000581728 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031848 |
protection from non-homologous end joining at telomere |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2156057 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006303 |
double-strand break repair via nonhomologous end joining |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000581728 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003684 |
damaged DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000581728 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0000784 |
nuclear chromosome, telomeric region |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000581728 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0001650 |
fibrillar center |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0035312 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0035312 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0036297 |
interstrand cross-link repair |
Reactome:R-HSA-6783310 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-HSA-6785986 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051301 |
cell division |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sengerová, B et al. (2012) Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases. J. Biol. Chem. 287 26254-67 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page