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Category:Team Amino Acid

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
requireschangesHUMAN:TIGARMegan.Bosson, Team Amino Acid2013-04-14 17:31:34 CDTGO:0070585 protein localization to mitochondrion (P)PMID:23185017ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows Relocalization of TIGAR to mitochondria during hypoxia

challenge
updatedbyinstructorDANRE:B9D2Megan.Bosson, Team Amino Acid2013-04-14 16:37:23 CDTGO:0007163 establishment or maintenance of cell polarity (P)PMID:21602787ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7 shows b9d2 contribute to the formation of planar cell polarity in mechanosensory epithelia.

challenge
updatedbyinstructorDANRE:INVSMegan.Bosson, Team Amino Acid2013-04-14 16:06:53 CDTGO:0005929 cilium (C)PMID:21602787ECO:0000314 direct assay evidence used in manual assertion

Figure 5- b9d2 and fleer contribute to the ciliary localization of Inversin.

challenge
updatedbyinstructorDANRE:B9D2Megan.Bosson, Team Amino Acid2013-04-14 15:58:03 CDTGO:0036372 opsin transport (P)PMID:21602787ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4 b9d2 function in ciliary trafficking of opsin

challenge
updatedbyinstructorDANRE:B9D2Megan.Bosson, Team Amino Acid2013-04-14 15:51:40 CDTGO:0042384 cilium assembly (P)PMID:21602787ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 shows b9d2 functions in ciliogenesis

challenge
requireschangesHUMAN:PLK1Megan.Bosson, Team Amino Acid2013-04-14 15:38:46 CDTGO:0051179 localization (P)PMID:22701722ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows Plk1 colocalizes with NPHP1 at the base of the cilium.

challenge
acceptableHUMAN:PLK1Megan.Bosson, Team Amino Acid2013-04-14 14:51:37 CDTGO:0006468 protein phosphorylation (P)PMID:22701722ECO:0000314 direct assay evidence used in manual assertion

Figure 3 shows Plk1 directly phosphorylates NPHP1 in vitro.

challenge
requireschangesHUMAN:FOLR1Megan.Bosson, Team Amino Acid2013-04-14 00:43:33 CDTGO:0005667 transcription factor complex (C)PMID:23243496ECO:0000314 direct assay evidence used in manual assertion

Figure 2 and 3 show FRα acting as a transcription factor

challenge
acceptableHUMAN:FOLR1Megan.Bosson, Team Amino Acid2013-04-14 00:14:23 CDTGO:0005634 nucleus (C)PMID:23243496ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows nuclear localization of FRα.

challenge
acceptableHUMAN:ANM5Megan.Bosson, Team Amino Acid2013-04-13 22:26:14 CDTGO:0005737 cytoplasm (C)PMID:22952863ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows PRMT5 localized in the cytoplasm

challenge
unacceptableMOUSE:KSYKMegan.Bosson, Team Amino Acid2013-04-13 21:47:00 CDTGO:1900180 regulation of protein localization to nucleus (P)PMID:23071339ECO:0000314 direct assay evidence used in manual assertion

Figure 3 shows Wild Type vs. Mutant IK (Ikaros)proteins. In contrast to wild-type IK, SYK-resistant IK protein M1-1 carrying A-mutations at both SYK phosphorylation sites showed no detectable nuclear localization when overexpressed in 293T cells

challenge
updatedbyinstructorSTRCO:FTSZSadie.jones, Team Amino Acid2013-04-10 09:30:12 CDTGO:0000935 barrier septum (C)PMID:19156202ECO:0000314 direct assay evidence used in manual assertion

Figure 3: Shows an addition localization pattern

challenge
acceptableMYCGE:FTSZSadie.jones, Team Amino Acid2013-04-09 16:29:54 CDTGO:0051301 cell division (P)PMID:20735775ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3&4: Show the difference in the wild type and the mutant

challenge

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Pages in category "Team Amino Acid"

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