User:Alana.Cheplowitz

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	DEIRA:CATA	2013-03-28 12:55:29 CDT	GO:0004096 catalase activity (F)	PMID:23365666	ECO:0000314 direct assay evidence used in manual assertion	Figure 4A shows that dGMP increased the activity of KatA.	challenge
unacceptable	STRCO:LANSB	2013-04-11 11:59:54 CDT	GO:0043581 mycelium development (P)	PMID:22309453	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2a,b, and c. Shows that SapB is required for differentiation in high osmolarity media.	challenge
unacceptable	STRCH:Q7AY50	2013-04-14 17:30:11 CDT	GO:0043581 mycelium development (P)	PMID:22309453	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 3. shows that the rodlet layer is important for differentiation in high osmolarity media	challenge
unacceptable	STRCH:Q934F8	2013-04-14 17:32:27 CDT	GO:0043581 mycelium development (P)	PMID:22309453	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 3. Shows that the rodlet layer is important for differentiation in high osmolarity media.	challenge
unacceptable	STRCH:Q53820	2013-04-14 17:35:07 CDT	GO:0043581 mycelium development (P)	PMID:22309453	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3. Shows that ramR is required for aerial mycelium development on high osmolarity media in S. coelicolor	challenge

acceptable:1
unacceptable:4
requires_changes:0
flagged:0

Annotations challenged by Alana.Cheplowitz

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Alana.Cheplowitz

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My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	STRCO:Q9RCY2	2012-10-04 16:07:32 CDT	GO:0043934 sporulation (P)	PMID:22753061	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1	challenge
unacceptable	STRCO:Q9L1J8	2012-10-18 13:07:48 CDT	GO:0007165 signal transduction (P)	PMID:12832397	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 6. Shows that deletion of the chaplin genes causes severe delays in aerial hyphae formation.	challenge
acceptable	STRCO:Q9Z584	2012-10-18 13:07:00 CDT	GO:0004112 cyclic-nucleotide phosphodiesterase activity (F)	PMID:22753061	ECO:0000314 direct assay evidence used in manual assertion	Figure 5. Correctly shows that RmdA has PDE activiy because it is has increase in swimming zones in semisolid agar of E. coli strain MG1655 yhjH with MBP-RmdA and MBP-RmdB.	challenge
unacceptable	STRCO:Q9Z584	2012-10-18 13:07:00 CDT	GO:0043581 mycelium development (P)	PMID:22753061	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 1. Shows the effects on the morphology of S. coelicolor from the inactivation of RmdA and RmdB.	challenge
unacceptable	STRCO:Q8CJY7	2012-11-13 09:16:45 CST	GO:0043581 mycelium development (P)	PMID:12832397	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 6. Shows that loss of chpA (in a chpA,C,D,H quadruple knockout) delayed aerial hyphae formation and sporulation.	challenge
unacceptable	STRCO:Q9AD93	2012-11-13 09:16:08 CST	GO:0043581 mycelium development (P)	PMID:12832397	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 6. Shows that the loss of chpC (in a chpA, C, D, H quadruple knockout) had delayed aerial hyphae formation and sporulaion.	challenge
unacceptable	STRCO:Q9L1J9	2012-11-15 14:50:53 CST	GO:0043581 mycelium development (P)	PMID:12832397	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 6. Shows that the loss of chpD (in a chpA, C, D, H quadruple knockout) had delayed aerial hyphae formation and sporulaion	challenge
unacceptable	STRCO:Q9AD92	2012-11-15 15:18:10 CST	GO:0043581 mycelium development (P)	PMID:12832397	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 6. Shows that the loss of chpH (in a chpA, C, D, H quadruple knockout) had delayed aerial hyphae formation and sporulaion.	challenge
unacceptable	STRCO:Q9X9Z2	2012-11-16 15:09:48 CST	GO:0043581 mycelium development (P)	PMID:15546671	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 7. Shows that ChpE is expressed during mycelium formation, these proteins are presumed to form a film that reduces water surface tension and allows hyphal protrusion into the air.	challenge
unacceptable	STRCO:Q9AD92	2012-11-16 15:07:49 CST	GO:0043581 mycelium development (P)	PMID:15546671	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 7. Shows that ChpH is expressed during mycelium formation, these proteins are presumed to form a film that reduces water surface tension and allows hyphal protrusion into the air	challenge
unacceptable	STRCO:Q9Z584	2012-11-17 09:28:31 CST	GO:0004112 cyclic-nucleotide phosphodiesterase activity (F)	PMID:22753061	ECO:0000314 direct assay evidence used in manual assertion	Figure 5. Correctly shows that RmdB has PDE activiy because it is has increase in swimming zones in semisolid agar of E. coli strain MG1655 yhjH with MBP-RmdA and MBP-RmdB	challenge
unacceptable	STRCO:Q9X7U2	2012-11-17 14:26:30 CST	GO:0043581 mycelium development (P)	PMID:12832397	ECO:0000316 genetic interaction evidence used in manual assertion	Figure 6. Shows a that more severe phenotype was seen when an additional deletion removed the last remaining sortase-targeted chaplin gene, chpB, to generate a chpA,B,C,D,H quintuple mutant, with a greater delay in aerial hyphae formation, and an almost complete lack of sporulation	challenge

acceptable:1
unacceptable:11
requires_changes:0
flagged:0

Annotations challenged by Alana.Cheplowitz

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
requireschanges	Curtis.baker, Team Roll Tide	HUMAN:AAKB2	GO:0004679 - AMP-activated protein kinase activity (P)	PMID:19639604	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 4

0 annotations fixed by Alana.Cheplowitz