STRMU:NAGB

Species (Taxon ID)	Streptococcus mutans serotype c (strain ATCC 700610 / UA159). (210007)
Gene Name(s)	nagB (ECO:0000255 with HAMAP-Rule:MF_01241)
Protein Name(s)	Glucosamine-6-phosphate deaminase (ECO:0000255 with HAMAP-Rule:MF_01241) GlcN6P deaminase (ECO:0000255 with HAMAP-Rule:MF_01241) GNPDA (ECO:0000255 with HAMAP-Rule:MF_01241) Glucosamine-6-phosphate isomerase (ECO:0000255 with HAMAP-Rule:MF_01241)
External Links
UniProt	Q8DV70
EMBL	AE014133
RefSeq	NP_721064.1
PDB	2RI0 2RI1
PDBsum	2RI0 2RI1
ProteinModelPortal	Q8DV70
SMR	Q8DV70
STRING	210007.SMU.636
EnsemblBacteria	AAN58370
GeneID	1028070
KEGG	smu:SMU_636
PATRIC	19663459
eggNOG	COG0363
KO	K02564
OMA	SELYSVN
OrthoDB	EOG6WX4S3
PhylomeDB	Q8DV70
BioCyc	SMUT210007:GC7Z-620-MONOMER
UniPathway	UPA00629
EvolutionaryTrace	Q8DV70
Proteomes	UP000002512
GO	GO:0004342 GO:0016787 GO:0006040 GO:0005975 GO:0006044 GO:0019262
HAMAP	MF_01241
InterPro	IPR006148 IPR004547
PANTHER	PTHR11280
Pfam	PF01182

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006040	amino sugar metabolic process	PMID:22438919	ECO:0000314			P		Figure 2 shows the addition of N-acetylglucosamine (GlcNAc)increases the expression of NagB but decreases the expression of GlmS, a gene which functionally opposes that of NagB. GlmS is known to be a key factor affecting the entrance of amino sugars into glycolysis and cell wall synthesis in several other bacteria, however their roles in S. mutans remain unclear. This paper, and specifically figure 2, confirms this function in S. mutans as well.	complete CACAO 7620
involved_in	GO:0006040	amino sugar metabolic process	PMID:22438919	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004342	glucosamine-6-phosphate deaminase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004547	F		Seeded From UniProt	complete
involved_in	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006148	P		Seeded From UniProt	complete
involved_in	GO:0006044	N-acetylglucosamine metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004547	P		Seeded From UniProt	complete
enables	GO:0004342	glucosamine-6-phosphate deaminase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.5.99.6	F		Seeded From UniProt	complete
involved_in	GO:0006044	N-acetylglucosamine metabolic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000337880	P		Seeded From UniProt	complete
enables	GO:0004342	glucosamine-6-phosphate deaminase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000337880	F		Seeded From UniProt	complete
involved_in	GO:0005975	carbohydrate metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0119	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
involved_in	GO:0019262	N-acetylneuraminate catabolic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00629	P		Seeded From UniProt	complete
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References

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