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DANRE:B0R0V8

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000113453)
External Links
UniProt B0R0V8
EMBL AL929096
AL929271
RefSeq NP_001278637.1
UniGene Dr.7421
Ensembl ENSDART00000099043
ENSDART00000145681
GeneID 286779
KEGG dre:286779
CTD 51606
ZFIN ZDB-GENE-021219-2
eggNOG COG5231
GeneTree ENSGT00390000003289
HOGENOM HOG000007240
HOVERGEN HBG000459
KO K02144
OMA DTLQENH
Reactome REACT_201955
REACT_220329
REACT_246915
PRO PR:B0R0V8
Proteomes UP000000437
GO GO:0000221
GO:0046961
GO:0015991
GO:0060041
Gene3D 1.25.10.10
1.25.40.150
InterPro IPR011989
IPR016024
IPR004908
IPR011987
PANTHER PTHR10698
Pfam PF11698
PF03224
PIRSF PIRSF032184
SUPFAM SSF48371

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0061075

positive regulation of neural retina development

PMID:18836173[1]

IMP: Inferred from Mutant Phenotype

P

Fig. 7 and Fig. 8 show that the v-ATPase mutants display defects in cell proliferation and increased levels of apoptosis which demonstrates its role in the proper development of the neural retina.

complete
CACAO 7275

GO:0048069

positive regulation of eye pigmentation

PMID:18836173[1]

IMP: Inferred from Mutant Phenotype

P

Fig 5

complete
CACAO 7276

GO:0000221

vacuolar proton-transporting V-type ATPase, V1 domain

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004908
InterPro:IPR011987

C

Seeded From UniProt

complete

GO:0015991

ATP hydrolysis coupled proton transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004908
InterPro:IPR011987

P

Seeded From UniProt

complete

GO:0016820

hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011987

F

Seeded From UniProt

complete

GO:0046961

proton-transporting ATPase activity, rotational mechanism

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004908

F

Seeded From UniProt

complete

GO:0048069

eye pigmentation

PMID:18836173[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060041

retina development in camera-type eye

PMID:15716491[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-020426-40

P

Seeded From UniProt

complete

GO:0061075

positive regulation of neural retina development

PMID:18836173[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Nuckels, RJ et al. (2009) The vacuolar-ATPase complex regulates retinoblast proliferation and survival, photoreceptor morphogenesis, and pigmentation in the zebrafish eye. Invest. Ophthalmol. Vis. Sci. 50 893-905 PubMed GONUTS page
  2. Gross, JM et al. (2005) Identification of zebrafish insertional mutants with defects in visual system development and function. Genetics 170 245-61 PubMed GONUTS page