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Category:Team Fanny Pack Eradication

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorKLEP3:APBE1Drumhel2, Team Fanny Pack Eradication2013-04-14 11:47:10 CDTGO:0017013 protein flavinylation (P)PMID:23558683ECO:0000314 direct assay evidence used in manual assertion

Figure 7.

challenge
acceptableSTRMU:NAGBDrumhel2, Team Fanny Pack Eradication2013-04-11 10:59:49 CDTGO:0006040 amino sugar metabolic process (P)PMID:22438919ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows the addition of N-acetylglucosamine (GlcNAc)increases the expression of NagB but decreases the expression of GlmS, a gene which functionally opposes that of NagB. GlmS is known to be a key factor affecting the entrance of amino sugars into glycolysis and cell wall synthesis in several other bacteria, however their roles in S. mutans remain unclear. This paper, and specifically figure 2, confirms this function in S. mutans as well.

challenge
updatedbyinstructorSTRMU:Q8DWM3Drumhel2, Team Fanny Pack Eradication2013-04-11 10:04:59 CDTGO:0044011 single-species biofilm formation on inanimate substrate (P)PMID:21078847ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 4A/4B shows that biofilm formation on glass surfaces was impaired in GbpB knockdown mutants.

challenge
requireschangesMOUSE:JAK2Mcgeedev, Team Fanny Pack Eradication2013-03-31 10:11:08 CDTGO:0019221 cytokine-mediated signaling pathway (P)PMID:23526587ECO:0000314 direct assay evidence used in manual assertion

JAK2 is essential to naive t cell homing. Figure 2C demonstrates that silencing JAK1/2 proteins severely inhibited the ability of chemokine-mediated t cell signaling. This indicated by the naive t-cell's inability to migrate through a chemokine gradient.

challenge

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Pages in category "Team Fanny Pack Eradication"

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