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User:Cwolterman

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorHUMAN:IL42013-02-08 21:37:38 CSTGO:0010633 negative regulation of epithelial cell migration (P)PMID:11698262ECO:0000314 direct assay evidence used in manual assertion

Figure 7 shows that Interleukin-4 (IL-4) inhibits the migration of the Calu-3 epithelial cells, but it does not directly prove the inhibition of wound healing.

challenge
updatedbyinstructorHUMAN:IFNG2013-02-08 21:55:19 CSTGO:0010634 positive regulation of epithelial cell migration (P)PMID:11698262ECO:0000314 direct assay evidence used in manual assertion

Based of figure 7 and figure 8 wound healing of Calu-3 epithelial lung cells is enhanced by Interferon (IFN)-γ (Interferon gamma).

challenge
acceptableHUMAN:APOC22013-02-09 15:30:34 CSTGO:0060230 lipoprotein lipase activator activity (F)PMID:270715ECO:0000314 direct assay evidence used in manual assertion

Based on figure 4 and figure 5 activity of Lipoprotein Lipase (LPL) was enhanced by Apolipoprotein C-II (apoC-II)

challenge
unacceptableMOUSE:ACTH2013-02-10 13:34:58 CSTGO:0043415 positive regulation of skeletal muscle tissue regeneration (P)PMID:18650267ECO:0000314 direct assay evidence used in manual assertion

Based on figure 6 knockout mice (alpha-actin-3 deficient)show an increased amount of EDL muscle recovery.

challenge
updatedbyinstructorHUMAN:MBB1A2013-02-10 13:40:02 CSTGO:2000210 positive regulation of anoikis (P)PMID:23388179ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3. MYBBP1A induces anoikis in normal breast and breast cancer cells through siRNA knockdown.

challenge

acceptable:1
unacceptable:1
requires_changes:0
flagged:0

Annotations challenged by Cwolterman

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
acceptableKgreene,
Team Science Dance
HUMAN:NEK8GO:0005929 - cilium (C)PMID:18199800ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3
acceptableMegatron,
Team Cybertron
DROME:GPDAGO:0006067 - ethanol metabolic process (P)PMID:19033156ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
requireschangesKthornhill,
Team Genetic Ninjas
MOUSE:PLCZ1GO:0071695 - anatomical structure maturation (P)PMID:17933795ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
updatedbyinstructorKpatel,
Team Llamarmy
DANRE:Q7ZU02GO:0008283 - cell population proliferation (P)PMID:22782722ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3

fixed by Cwolterman
correctedthroughchallengesSbutler,
Team Thundercats Ho!
HUMAN:KSYKGO:0006468 - protein phosphorylation (P)PMID:18818202ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4

fixed by Cwolterman

2 annotations fixed by Cwolterman

What do the icons mean in the status column?

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