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User:Kgreene

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableMOUSE:TRPS12013-02-08 17:19:41 CSTGO:0045892 negative regulation of transcription, DNA-dependent (P)PMID:23133399ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3: qRT-PCR show increased SOX9 expression in the vibrissae follicles in mice with mutant TRPS1.

challenge
unacceptableMOUSE:SOX52013-02-08 20:51:20 CSTGO:0060425 lung morphogenesis (P)PMID:21330457ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2 shows p-values of less than 0.01 of associated genotyped SNPs with COPD

challenge
acceptableHUMAN:NEK82013-02-08 21:46:03 CSTGO:0005929 cilium (C)PMID:18199800ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 shows that mutant forms of NEK8 have defects in cillia localization.

challenge
acceptableRAT:HAX12013-02-08 22:08:25 CSTGO:0016529 sarcoplasmic reticulum (C)PMID:19920172ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows HAX-1 overexpression or downregulation effects on on rat cardiomyocyte contractile function.

challenge
acceptableMOUSE:HAX12013-02-08 22:12:15 CSTGO:0016529 sarcoplasmic reticulum (C)PMID:19920172ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows the effects of cardiac-specific HAX-1 overexpressing in mice.

challenge
acceptableMOUSE:TRPS12013-02-10 17:08:57 CSTGO:0001942 hair follicle development (P)PMID:23133399ECO:0000315 mutant phenotype evidence used in manual assertion

Figures 1-3: show decreased hair follicle growth in mice with mutant TRPS1.

challenge

acceptable:5
unacceptable:1
requires_changes:0
flagged:0

Annotations challenged by Kgreene

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Kgreene

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