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RAT:HAX1

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Hax1 (synonyms: Hs1bp1)
Protein Name(s) HCLS1-associated protein X-1

HS1-associating protein X-1 HAX-1 HS1-binding protein 1 HSP1BP-1

External Links
UniProt Q7TSE9
EMBL AY291062
AY291063
AY291064
AY919342
AY919343
DQ286293
RefSeq NP_853658.1
UniGene Rn.185269
IntAct Q7TSE9
STRING 10116.ENSRNOP00000055866
PaxDb Q7TSE9
PRIDE Q7TSE9
DNASU 291202
GeneID 291202
KEGG rno:291202
CTD 10456
RGD 727960
eggNOG NOG45051
HOVERGEN HBG002991
InParanoid Q7TSE9
KO K16220
PhylomeDB Q7TSE9
NextBio 632255
PRO PR:Q7TSE9
Proteomes UP000002494
ExpressionAtlas Q7TSE9
Genevestigator Q7TSE9
GO GO:0015629
GO:0016324
GO:0030136
GO:0043231
GO:0030027
GO:0005739
GO:0031965
GO:0016529
GO:0005667
GO:0019904
GO:0071345
GO:2000251
GO:0030854
GO:0033138
GO:0050731
GO:0014068
GO:0051897
GO:0045944
GO:0030833
InterPro IPR017248
PIRSF PIRSF037634

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016529

sarcoplasmic reticulum

PMID:19920172[1]

ECO:0000314

C

Figure 1 shows HAX-1 overexpression or downregulation effects on on rat cardiomyocyte contractile function.

complete
CACAO 6417

part_of

GO:0016529

sarcoplasmic reticulum

PMID:19920172[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

PMID:15159385[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030136

clathrin-coated vesicle

PMID:15159385[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0019904

protein domain specific binding

PMID:15159385[2]

ECO:0000353

physical interaction evidence used in manual assertion

RGD:619930
RGD:619951
RGD:620248

F

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:15159385[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017248

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256
UniProtKB-SubCell:SL-0095

C

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0968

C

Seeded From UniProt

complete

part_of

GO:0016529

sarcoplasmic reticulum

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0703
UniProtKB-SubCell:SL-0239

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496
UniProtKB-SubCell:SL-0173

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0031965

nuclear membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0182

C

Seeded From UniProt

complete

part_of

GO:0000932

P-body

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0230

C

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0138

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Zhao, W et al. (2009) The anti-apoptotic protein HAX-1 is a regulator of cardiac function. Proc. Natl. Acad. Sci. U.S.A. 106 20776-81 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Ortiz, DF et al. (2004) Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells. J. Biol. Chem. 279 32761-70 PubMed GONUTS page