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MOUSE:ACTH

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Actg2 (synonyms: Acta3, Actsg)
Protein Name(s) Actin, gamma-enteric smooth muscle

Alpha-actin-3 Gamma-2-actin Smooth muscle gamma-actin

External Links
UniProt P63268
EMBL M26689
BC002042
CCDS CCDS51822.1
PIR A32788
RefSeq NP_033740.2
UniGene Mm.292865
ProteinModelPortal P63268
SMR P63268
BioGrid 197947
IntAct P63268
MINT MINT-4086768
STRING 10090.ENSMUSP00000113552
PhosphoSite P63268
MaxQB P63268
PaxDb P63268
PRIDE P63268
Ensembl ENSMUST00000075161
ENSMUST00000121731
GeneID 11468
KEGG mmu:11468
UCSC uc009cnr.1
CTD 72
MGI MGI:104589
eggNOG COG5277
HOGENOM HOG000233340
HOVERGEN HBG003771
InParanoid P63268
KO K12315
OMA PXEREIV
OrthoDB EOG72RMZ1
PhylomeDB P63268
TreeFam TF354237
Reactome REACT_235059
NextBio 278796
PRO PR:P63268
Proteomes UP000000589
Bgee P63268
CleanEx MM_ACTG2
ExpressionAtlas P63268
Genevestigator P63268
GO GO:0072562
GO:0071944
GO:0005737
GO:0005856
GO:0005524
InterPro IPR004000
IPR020902
IPR004001
PANTHER PTHR11937
Pfam PF00022
PRINTS PR00190
SMART SM00268
PROSITE PS00406
PS00432
PS01132

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043415

positive regulation of skeletal muscle tissue regeneration

PMID:18650267[1]

ECO:0000314

P

Based on figure 6 knockout mice (alpha-actin-3 deficient)show an increased amount of EDL muscle recovery.

complete
CACAO 6536

part_of

GO:0032982

myosin filament

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:F1P476

C

Seeded From UniProt

complete

involved_in

GO:0090131

mesenchyme migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

P

has_regulation_target:(UniProtKB:E1C3A6)

Seeded From UniProt

complete

part_of

GO:0044297

cell body

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P08023

C

part_of:(CL:0000134)

Seeded From UniProt

complete

part_of

GO:0071944

cell periphery

PMID:12040017[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Chan, S et al. (2008) A gene for speed: contractile properties of isolated whole EDL muscle from an alpha-actinin-3 knockout mouse. Am. J. Physiol., Cell Physiol. 295 C897-904 PubMed GONUTS page
  2. Shillingford, JM et al. (2002) Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis. Mol. Endocrinol. 16 1309-21 PubMed GONUTS page