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DANRE:Q7ZU02

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) Chemokine (C-X-C motif) receptor 4a (ECO:0000313 with EMBL:AAH50172.1)
External Links
UniProt Q7ZU02
EMBL BC050172
RefSeq NP_571957.2
UniGene Dr.84258
ProteinModelPortal Q7ZU02
STRING 7955.ENSDARP00000074800
GeneID 140747
KEGG dre:140747
CTD 140747
ZFIN ZDB-GENE-020102-1
eggNOG NOG328039
HOGENOM HOG000234122
HOVERGEN HBG106917
KO K04189
NextBio 20797039
GO GO:0016021
GO:0016494
GO:0006935
GO:0042119
InterPro IPR001277
IPR000355
IPR000276
IPR017452
PANTHER PTHR24227
PTHR24227:SF7
Pfam PF00001
PRINTS PR00657
PR00645
PR00237
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004871

signal transducer activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

Seeded From UniProt

complete

GO:0004930

G-protein coupled receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276

F

Seeded From UniProt

complete

GO:0004930

G-protein coupled receptor activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

GO:0004950

chemokine receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000355

F

Seeded From UniProt

complete

GO:0006935

chemotaxis

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000355
InterPro:IPR001277

P

Seeded From UniProt

complete

GO:0007165

signal transduction

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276
InterPro:IPR000355
InterPro:IPR001277

P

Seeded From UniProt

complete

GO:0008283

cell proliferation

PMID:22782722[1]

IMP: Inferred from Mutant Phenotype

P

Figure 3: Results show that Cxcr4a is essential for endodermal cell proliferation

complete
CACAO 6486

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

GO:0008283

cell proliferation

PMID:22782722[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276
InterPro:IPR000355
InterPro:IPR001277
InterPro:IPR017452

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0016494

C-X-C chemokine receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001277

F

Seeded From UniProt

complete

GO:0042119

neutrophil activation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001277

P

Seeded From UniProt

complete

GO:0070098

chemokine-mediated signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000355

P

Seeded From UniProt

complete

GO:0070098

chemokine-mediated signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001277

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Stückemann, T et al. (2012) Zebrafish Cxcr4a determines the proliferative response to Hedgehog signalling. Development 139 2711-20 PubMed GONUTS page