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Category:GO:0090399 ! replicative senescence
name: replicative senescence
namespace: biological_process
def: "The process by which normal somatic cells reach an irreversible stage of cell cycle arrest following multiple rounds of replication; this end stage is associated with marked changes in gene expression and function. This is a natural barrier to unlimited proliferation of somatic cells, and is believed to be contolled by telomere shortening." [PMID:17014937, PMID:23061726]
is_a: GO:0022402 ! cell cycle process
AmiGO
<GOterm>GO:0090399</GOterm>
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This category has the following 2 subcategories, out of 2 total.
