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HUMAN:WNT16
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | WNT16 | |
| Protein Name(s) | Protein Wnt-16 | |
| External Links | ||
| UniProt | Q9UBV4 | |
| EMBL | AF169963 AF152584 AC006364 BC104919 BC104945 | |
| CCDS | CCDS5781.1 | |
| RefSeq | NP_057171.2 NP_476509.1 | |
| UniGene | Hs.272375 | |
| ProteinModelPortal | Q9UBV4 | |
| SMR | Q9UBV4 | |
| BioGrid | 119514 | |
| IntAct | Q9UBV4 | |
| STRING | 9606.ENSP00000222462 | |
| PhosphoSite | Q9UBV4 | |
| DMDM | 12643875 | |
| PaxDb | Q9UBV4 | |
| PRIDE | Q9UBV4 | |
| Ensembl | ENST00000222462 | |
| GeneID | 51384 | |
| KEGG | hsa:51384 | |
| UCSC | uc003vjw.3 | |
| CTD | 51384 | |
| GeneCards | GC07P120965 | |
| HGNC | HGNC:16267 | |
| HPA | HPA027030 | |
| MIM | 606267 | |
| neXtProt | NX_Q9UBV4 | |
| PharmGKB | PA38105 | |
| eggNOG | NOG238376 | |
| GeneTree | ENSGT00760000118943 | |
| HOGENOM | HOG000039529 | |
| HOVERGEN | HBG001595 | |
| InParanoid | Q9UBV4 | |
| KO | K01558 | |
| OMA | TCWKTMS | |
| OrthoDB | EOG7C8GJ8 | |
| PhylomeDB | Q9UBV4 | |
| TreeFam | TF105310 | |
| Reactome | REACT_163710 REACT_18372 | |
| SignaLink | Q9UBV4 | |
| GeneWiki | WNT16 | |
| GenomeRNAi | 51384 | |
| NextBio | 54895 | |
| PRO | PR:Q9UBV4 | |
| Proteomes | UP000005640 | |
| Bgee | Q9UBV4 | |
| CleanEx | HS_WNT16 | |
| ExpressionAtlas | Q9UBV4 | |
| Genevestigator | Q9UBV4 | |
| GO | GO:0005737 GO:0005576 GO:0005615 GO:0005578 GO:0005109 GO:0046849 GO:0060317 GO:0045165 GO:0030216 GO:0043616 GO:0060548 GO:0030182 GO:0003408 GO:0090403 GO:0010628 GO:0046330 GO:0014068 GO:0090399 GO:0016055 | |
| InterPro | IPR005817 IPR013304 IPR018161 | |
| PANTHER | PTHR12027 | |
| Pfam | PF00110 | |
| PRINTS | PR01895 PR01349 | |
| SMART | SM00097 | |
| PROSITE | PS00246 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0090403 |
oxidative stress-induced premature senescence |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090399 |
replicative senescence |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060548 |
negative regulation of cell death |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046330 |
positive regulation of JNK cascade |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043616 |
keratinocyte proliferation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030216 |
keratinocyte differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0003408 |
optic cup formation involved in camera-type eye development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045165 |
cell fate commitment |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98957 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030182 |
neuron differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000246517 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016055 |
Wnt signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0010194 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0004009 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005109 |
frizzled binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0004009 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060317 |
cardiac epithelial to mesenchymal transition |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9QYS1 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0046849 |
bone remodeling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9QYS1 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005102 |
signaling receptor binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016055 |
Wnt signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016055 |
Wnt signaling pathway |
Reactome:R-HSA-195721 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-3247843 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016055 |
Wnt signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Binet, R et al. (2009) WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway. Cancer Res. 69 9183-91 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Teh, MT et al. (2007) Role for WNT16B in human epidermal keratinocyte proliferation and differentiation. J. Cell. Sci. 120 330-9 PubMed GONUTS page
- ↑ Mazieres, J et al. (2005) Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene 24 5396-400 PubMed GONUTS page
- ↑ McWhirter, JR et al. (1999) Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. Proc. Natl. Acad. Sci. U.S.A. 96 11464-9 PubMed GONUTS page
- ↑ Fokina, VM & Frolova, EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev. Dyn. 235 496-505 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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