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CHICK:Q7ZT27

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CDKN2B (ECO:0000313 with Ensembl:ENSGALP00000042709)
Protein Name(s) P15INK4b tumor suppressor (ECO:0000313 with EMBL:AAN38849.1)

Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000042709) p15INK4b tumor suppressor (ECO:0000313 with EMBL:AAN38847.1)

External Links
UniProt Q7ZT27
EMBL AC195266
AY138246
AY138247
RefSeq NP_989764.1
UniGene Gga.5007
SMR Q7ZT27
Ensembl ENSGALT00000044862
GeneID 395076
KEGG gga:395076
CTD 1030
GeneTree ENSGT00390000004527
HOVERGEN HBG050870
KO K04685
OMA IGNHLWV
Reactome REACT_194991
REACT_208309
REACT_213542
REACT_214700
NextBio 20815169
PRO PR:Q7ZT27
Proteomes UP000000539
GO GO:2000134
GO:0048536
Gene3D 1.25.40.20
InterPro IPR002110
IPR020683
Pfam PF12796
SMART SM00248
SUPFAM SSF48403
PROSITE PS50297

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001948826
RGD:2324
UniProtKB:P42771
UniProtKB:P42772
UniProtKB:P55273

C

Seeded From UniProt

complete

enables

GO:0004861

cyclin-dependent protein serine/threonine kinase inhibitor activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001948826
UniProtKB:P42771
UniProtKB:P42772
UniProtKB:P55273

F

Seeded From UniProt

complete

involved_in

GO:2000774

positive regulation of cellular senescence

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0090399

replicative senescence

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0090398

cellular senescence

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

enables

GO:0051059

NF-kappaB binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

F

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0045736

negative regulation of cyclin-dependent protein serine/threonine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0042326

negative regulation of phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0035986

senescence-associated heterochromatin focus assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

part_of

GO:0035985

senescence-associated heterochromatin focus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

C

Seeded From UniProt

complete

involved_in

GO:0032088

negative regulation of NF-kappaB transcription factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0030308

negative regulation of cell growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

F

Seeded From UniProt

complete

involved_in

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0007265

Ras protein signal transduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0007050

cell cycle arrest

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

C

Seeded From UniProt

complete

enables

GO:0004861

cyclin-dependent protein serine/threonine kinase inhibitor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

F

Seeded From UniProt

complete

involved_in

GO:0001953

negative regulation of cell-matrix adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

involved_in

GO:0000082

G1/S transition of mitotic cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42771
ensembl:ENSP00000418915

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page