User:Rausch14

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	HUMAN:AT5F1	2014-04-03 11:44:33 CDT	GO:0045255 hydrogen-translocating F-type ATPase complex (C)	PMID:12110673	ECO:0000314 direct assay evidence used in manual assertion	Figure 2: the F1F0 complex is associated with the mitochondria and has ATP hydrolysis activity. Oligomycin inhibits the ATP hydrolysis activity of the protein complex by binding to complex active site.	challenge
acceptable	ARATH:OAT	2014-04-03 13:05:43 CDT	GO:0051646 mitochondrion localization (P)	PMID:18419821	ECO:0000314 direct assay evidence used in manual assertion	Figure 1: Leaf tissue from Arabidopsis was transformed with delta-OAT-GFP. GFP florescence was observed localized in mitochondria.	challenge
unacceptable	YEAST:CCW12	2014-04-03 19:26:22 CDT	GO:0044426 cell wall part (C)	PMID:17315267	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2: yeast mutants for ccw12 protein did not have as great of an observation density compared to ccw12 wild type yeast. This demonstrates that ccw12 is integral for cell wall stability and Yeast growth.	challenge
unacceptable	RAT:OPRM	2014-04-03 23:03:50 CDT	GO:0003924 GTPase activity (F)	PMID:16682964	ECO:0000314 direct assay evidence used in manual assertion	Figure 2a: In the presents of morphine, gene (marked with symbol mu) is found to bind to GTP. More GTP is bound when in presents of larger concentration of morphine.	challenge
unacceptable	RAT:OPRM	2014-04-03 23:25:38 CDT	GO:0010975 regulation of neuron projection development (P)	PMID:16682965	ECO:0000314 direct assay evidence used in manual assertion	Figure 5: interactions of Oprm1 (designated by symbol mu in figure) in the presence of morphine is observed to increase number of cells with neurite development. Neurite development in cells increase as morphine dose increases.	challenge
updatedbyinstructor	RAT:CNR1	2014-04-04 00:06:20 CDT	GO:0045121 membrane raft (C)	PMID:21895628	ECO:0000314 direct assay evidence used in manual assertion	Figure 6c: Alignment was observed between CTBs (lipid rafts)marked with red florescent proteins and the CB1 (cannabinoid receptor 1) marked with GFP. This suggests that CB1 is a membrane bound protein associated with lipid rafts.	challenge
acceptable	HUMAN:TAAR1	2014-04-04 01:13:27 CDT	GO:0004930 G-protein coupled receptor activity (F)	PMID:11723224	ECO:0000314 direct assay evidence used in manual assertion	Figure 2B: Gene TAAR1 produces cAMP in the presence of MDMA. Greater Concentrations of MDMA lead to greater level of cAMP produced. HEK293 cells lineage utilized for direct assay testing.	challenge

acceptable:2
unacceptable:4
requires_changes:0
flagged:0

Annotations challenged by Rausch14

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Fclingen, Team What the Fox Says	ECOLI:LAMB	GO:0015288 - porin activity (F)	PMID:24412198	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 4
updatedbyinstructor	Hylandth, MichSt14A 37	ARATH:PLAS2	GO:0046028 - electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity (F)	PMID:12773541	ECO:0000316 genetic interaction evidence used in manual assertion	challenge	C: 2
unacceptable	Jonathanc, Team Rubby ducky	VIBF1:Q5E614	GO:0016747 - acyltransferase activity, transferring groups other than amino-acyl groups (F)	PMID:18487321	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1

0 annotations fixed by Rausch14

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