GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:AT5F1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ATP5F1 | |
| Protein Name(s) | ATP synthase F(0) complex subunit B1, mitochondrial
ATP synthase proton-transporting mitochondrial F(0) complex subunit B1 ATP synthase subunit b ATPase subunit b | |
| External Links | ||
| UniProt | P24539 | |
| EMBL | X60221 AL390195 BC005366 BC005960 BC016350 | |
| CCDS | CCDS836.1 | |
| PIR | JQ1144 | |
| RefSeq | NP_001679.2 | |
| UniGene | Hs.514870 | |
| ProteinModelPortal | P24539 | |
| SMR | P24539 | |
| BioGrid | 107000 | |
| IntAct | P24539 | |
| MINT | MINT-3010280 | |
| STRING | 9606.ENSP00000358737 | |
| PhosphoSite | P24539 | |
| DMDM | 20455474 | |
| MaxQB | P24539 | |
| PaxDb | P24539 | |
| PeptideAtlas | P24539 | |
| PRIDE | P24539 | |
| Ensembl | ENST00000369722 | |
| GeneID | 515 | |
| KEGG | hsa:515 | |
| UCSC | uc001ebc.3 | |
| CTD | 515 | |
| GeneCards | GC01P111991 | |
| HGNC | HGNC:840 | |
| HPA | HPA046067 | |
| MIM | 603270 | |
| neXtProt | NX_P24539 | |
| PharmGKB | PA25130 | |
| eggNOG | NOG245616 | |
| HOGENOM | HOG000007163 | |
| HOVERGEN | HBG050604 | |
| InParanoid | P24539 | |
| KO | K02127 | |
| OMA | VINHETF | |
| OrthoDB | EOG7V4B02 | |
| PhylomeDB | P24539 | |
| TreeFam | TF313250 | |
| Reactome | REACT_6759 | |
| GeneWiki | ATP5F1 | |
| GenomeRNAi | 515 | |
| NextBio | 2135 | |
| PRO | PR:P24539 | |
| Proteomes | UP000005640 | |
| Bgee | P24539 | |
| CleanEx | HS_ATP5F1 | |
| ExpressionAtlas | P24539 | |
| Genevestigator | P24539 | |
| GO | GO:0070062 GO:0016020 GO:0005743 GO:0005759 GO:0005753 GO:0000276 GO:0005739 GO:0005634 GO:0015078 GO:0022857 GO:0006200 GO:0015986 GO:0044237 GO:0042776 GO:0022904 GO:0044281 GO:0021762 | |
| InterPro | IPR008688 IPR013837 | |
| PANTHER | PTHR12733 | |
| Pfam | PF05405 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0021762 |
substantia nigra development |
ECO:0007007 |
high throughput expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0045255 |
hydrogen-translocating F-type ATPase complex |
ECO:0000314 |
C |
Figure 2: the F1F0 complex is associated with the mitochondria and has ATP hydrolysis activity. Oligomycin inhibits the ATP hydrolysis activity of the protein complex by binding to complex active site. |
complete | |||||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001134) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000019) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042776 |
mitochondrial ATP synthesis coupled proton transport |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005753 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0022857 |
transmembrane transporter activity |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005753 |
F |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0016887 |
ATPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005753 |
mitochondrial proton-transporting ATP synthase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000296496 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0015986 |
ATP synthesis coupled proton transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000296496 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000276 |
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000296496 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0099132 |
ATP hydrolysis coupled cation transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0046933 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000276 |
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015078 |
proton transmembrane transporter activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015986 |
ATP synthesis coupled proton transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042776 |
mitochondrial ATP synthesis coupled proton transport |
Reactome:R-HSA-164834 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042407 |
cristae formation |
Reactome:R-HSA-8949613 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006754 |
ATP biosynthetic process |
Reactome:R-HSA-164840 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
Reactome:R-HSA-8949580 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045263 |
proton-transporting ATP synthase complex, coupling factor F(o) |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
- ↑ Chen, S et al. (2012) Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis. Neurochem. Res. 37 2805-13 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Aggeler, R et al. (2002) A functionally active human F1F0 ATPase can be purified by immunocapture from heart tissue and fibroblast cell lines. Subunit structure and activity studies. J. Biol. Chem. 277 33906-12 PubMed GONUTS page
- ↑ Zhao, X et al. (2011) Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes. Mol. Cell Proteomics 10 M110.000299 PubMed GONUTS page
- ↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
- ↑ Higuti, T et al. (1991) Molecular cloning of cDNA for the import precursor of human subunit B of H(+)-ATP synthase in mitochondria. Biochem. Biophys. Res. Commun. 178 1014-20 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
a
m
o
p
- Primates
- GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism
- GO:0045263 ! proton-transporting ATP synthase complex, coupling factor F(o)
- GO:0015986 ! proton motive force-driven ATP synthesis
- GO:0042776 ! proton motive force-driven mitochondrial ATP synthesis
- GO:0015078 ! proton transmembrane transporter activity
