GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
|Status||Page||User||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|HUMAN:TAAR1||Rausch14, MichSt14A 18||2014-04-04 01:13:27 CDT||GO:0004930 G-protein coupled receptor activity (F)||PMID:11723224||ECO:0000314 direct assay evidence used in manual assertion|
Figure 2B: Gene TAAR1 produces cAMP in the presence of MDMA. Greater Concentrations of MDMA lead to greater level of cAMP produced. HEK293 cells lineage utilized for direct assay testing.
|RAT:CNR1||Rausch14, MichSt14A 18||2014-04-04 00:06:20 CDT||GO:0045121 membrane raft (C)||PMID:21895628||ECO:0000314 direct assay evidence used in manual assertion|
Figure 6c: Alignment was observed between CTBs (lipid rafts)marked with red florescent proteins and the CB1 (cannabinoid receptor 1) marked with GFP. This suggests that CB1 is a membrane bound protein associated with lipid rafts.
|RAT:OPRM||Rausch14, MichSt14A 18||2014-04-03 23:25:38 CDT||GO:0010975 regulation of neuron projection development (P)||PMID:16682965||ECO:0000314 direct assay evidence used in manual assertion|
Figure 5: interactions of Oprm1 (designated by symbol mu in figure) in the presence of morphine is observed to increase number of cells with neurite development. Neurite development in cells increase as morphine dose increases.
|RAT:OPRM||Rausch14, MichSt14A 18||2014-04-03 23:03:50 CDT||GO:0003924 GTPase activity (F)||PMID:16682964||ECO:0000314 direct assay evidence used in manual assertion|
Figure 2a: In the presents of morphine, gene (marked with symbol mu) is found to bind to GTP. More GTP is bound when in presents of larger concentration of morphine.
|YEAST:CCW12||Rausch14, MichSt14A 18||2014-04-03 19:26:22 CDT||GO:0044426 cell wall part (C)||PMID:17315267||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 2: yeast mutants for ccw12 protein did not have as great of an observation density compared to ccw12 wild type yeast. This demonstrates that ccw12 is integral for cell wall stability and Yeast growth.
|ARATH:OAT||Rausch14, MichSt14A 18||2014-04-03 13:05:43 CDT||GO:0051646 mitochondrion localization (P)||PMID:18419821||ECO:0000314 direct assay evidence used in manual assertion|
Figure 1: Leaf tissue from Arabidopsis was transformed with delta-OAT-GFP. GFP florescence was observed localized in mitochondria.
|HUMAN:AT5F1||Rausch14, MichSt14A 18||2014-04-03 11:44:33 CDT||GO:0045255 hydrogen-translocating F-type ATPase complex (C)||PMID:12110673||ECO:0000314 direct assay evidence used in manual assertion|
Figure 2: the F1F0 complex is associated with the mitochondria and has ATP hydrolysis activity. Oligomycin inhibits the ATP hydrolysis activity of the protein complex by binding to complex active site.
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Pages in category "MichSt14A 18"
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