User:Mcfadd48

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	STRMU:Y1061	2014-04-04 11:04:18 CDT	GO:0030695 GTPase regulator activity (F)	PMID:24659773	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4: An endpoint colorimetric assay indicated that the GTPase activity of Ffh alone, as well as that of Ffh/scRNA, was significantly increased upon addition of YlxM.	challenge
unacceptable	ENTFA:Q82ZP8	2014-04-04 11:16:34 CDT	GO:0033554 cellular response to stress (P)	PMID:22092815	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2 indicates that a slyA mutant strain is significantly impaired in its ability to grow under bile salt stress (in the presence of 0.08% bile salts), compared to wild-type E. faecalis	challenge
unacceptable	ENTFA:Q82ZP8	2014-04-04 11:16:34 CDT	GO:0033554 cellular response to stress (P)	PMID:22092815	ECO:0000314 direct assay evidence used in manual assertion	Figure 1 shows induction of slyA under bile salt stress conditions.	challenge
unacceptable	ANOGA:B2FXG9	2014-04-05 20:31:16 CDT	GO:0002218 activation of innate immune response (P)	PMID:16076953	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3A shows that silencing of either domain of REL2 results in significant reduction of CEC1 (Cecropin A) expression.	challenge
updatedbyinstructor	DICD3:E0SG24	2014-04-05 23:48:31 CDT	GO:0045892 negative regulation of transcription, DNA-templated (P)	PMID:22267675	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2A shows that in a slyA mutant, hrp genes controlling the Type 3 Secretion System are overexpressed.	challenge
updatedbyinstructor	XANOB:G7TJY8	2014-04-06 13:13:00 CDT	GO:0009405 pathogenesis (P)	PMID:24675748	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2A shows that a XOC_1550 mutant causes significantly shorter lesions, and Figure 2E shows that XOC_1550 mutant is impaired in its ability to grow in rice, identifying Xrp5 as a critical protein in pathogenesis	challenge
acceptable	AEDAE:Q534Q6	2014-04-06 13:58:06 CDT	GO:0002218 activation of innate immune response (P)	PMID:15722339	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4A shows transfection of REL1A alone can induce expression of Cecropin A and Defensin A in Aag2 cells. Figure 4D shows RNAi knockdown of REL1 decreases fungal infection survival in mosquitoes.	challenge
unacceptable	PSEAE:Q9HXI7	2014-04-06 16:30:36 CDT	GO:0006979 response to oxidative stress (P)	PMID:24466226	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 5 shows decreased survival under oxidative stress conditions in an iscR mutant. Tn7-borne expression of iscR in the iscR mutant restored survival percentage to that of wild-type P. aeruginosa.	challenge
unacceptable	ARATH:F4IU18	2014-04-06 17:44:22 CDT	GO:0000302 response to reactive oxygen species (Figure 7 shows that the rol5-1 mutant is hypersensitive to hydrogen peroxide and hyposensitive to the ROS scavenger CuCl2, indicating the importance of ROL5 in the sensing of and response to ROS.)	PMID:20530756	IMP: Inferred from Mutant Phenotype		challenge
acceptable	BACSU:MCPC	2014-04-06 17:55:15 CDT	GO:0050918 positive chemotaxis (P)	PMID:23038252	ECO:0000314 direct assay evidence used in manual assertion	Table 1 shows the results from a capillary assay, indicating that McpC alone can support chemotaxis to 17 amino acids.	challenge

acceptable:3
unacceptable:5
requires_changes:0
flagged:0

Annotations challenged by Mcfadd48

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Rizzomi2, MichSt14A 44	LISMO:Q8Y783	GO:0035635 - entry of bacterium into host cell (P)	PMID:24572033	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 2 fixed by Rizzomi2
updatedbyinstructor	Drl5141, Team Protein Titans	MOUSE:CD14	GO:0006898 - receptor-mediated endocytosis (P)	PMID:22078883	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3
unacceptable	Drl5141, Team Protein Titans	MOUSE:CD14	GO:0032720 - negative regulation of tumor necrosis factor production (P)	PMID:22078883	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1
unacceptable	Min.lorna, Team Ood	BUNYW:NSS	GO:0010629 - negative regulation of gene expression (P)	PMID:11209062	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2
updatedbyinstructor	Jiyan.Mohammad, Team Just Name It Something	SFV:POLS	GO:0019068 - virion assembly (P)	PMID:2200886	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2

0 annotations fixed by Mcfadd48

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