GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
|Status||Page||User||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|MOUSE:K22E||Kadeen.jennings, Team Nucleus||2013-04-14 17:54:53 CDT||GO:0005856 cytoskeleton (C)||PMID:23536778||ECO:0000314 direct assay evidence used in manual assertion|
|HUMAN:SPTN1||Whitney.rodriguez, Team Nucleus||2013-04-14 17:41:58 CDT||GO:0000723 telomere maintenance (P)||PMID:23571757||ECO:0000314 direct assay evidence used in manual assertion|
Fig 1 shows normal cells that have been transfected and treated for 24 hours with MMC. The arrows show sister chromatid fusions , breaks, and exchanges).(B) A score of 100 metaphase spreads scored for chromosomal aberrations
|MOUSE:BMP7||Madeline.rohl, Team Nucleus||2013-04-14 09:47:35 CDT||GO:0003416 endochondral bone growth (P)||PMID:23539268||ECO:0000316 genetic interaction evidence used in manual assertion|
Figure 1 shows response of cells to bone morphology protein.
|MOUSE:ALKB7||Abena.agyepong, Team Nucleus||2013-04-13 21:14:48 CDT||GO:0005759 mitochondrial matrix (C)||PMID:23572141||ECO:0000314 direct assay evidence used in manual assertion|
Figure 1 shows the subcellular localization of Alkbh7 in mouse.
|MOUSE:LEG3||Abena.agyepong, Team Nucleus||2013-04-13 19:13:16 CDT||GO:0009986 cell surface (C)||PMID:23576987||ECO:0000314 direct assay evidence used in manual assertion|
Gal-3 is known to be expressed on the cell surface of human Eos, but Mouse Eos express Gal-3 as well. Figure 2B shows cell surface expression of Gal-3 in non-permeabilized BM-derived Eos.
|HUMAN:COR1B||Abena.agyepong, Team Nucleus||2013-04-13 18:13:49 CDT||GO:0030036 actin cytoskeleton organization (P)||PMID:18775315||ECO:0000314 direct assay evidence used in manual assertion|
According to Figure 2C, in the presence of 50 nM Coronin 1B, total actin filament was reduced and branching was less extensive than in the control reactions.
|RAT:TGFB1||Abena.agyepong, Team Nucleus||2013-04-11 13:39:00 CDT||GO:0006468 protein phosphorylation (P)||PMID:23393573||ECO:0000314 direct assay evidence used in manual assertion|
According to Figure 8b, there was a 67%increase in phosphorylated FOXO1 in TGF- beta 1 treated cells compared to the levels in control treated cells. Moreover, Phosphorylation of FOXO1 in TGF-Beta 1 treated cells was inhibited in cells pretreated with P13K inhibitor.
|HUMAN:ZN330||Abena.agyepong, Team Nucleus||2013-04-10 19:09:51 CDT||GO:0008104 protein localization (P)||PMID:23516598||ECO:0000314 direct assay evidence used in manual assertion|
The nucleolar localization of Flag-NOA36 recombinant protein was confirmed using an anti-UBF antibody as nucleolar marker(Fig 2C. The nucleolar staining was not homogeneous, being localized mainly on the periphery of the nucleolus. From this data it is concluded that NOA36 contains at least one nucleolar localization signal.
|MOUSE:TUB||Abena.agyepong, Team Nucleus||2013-04-10 12:11:57 CDT||GO0021766 hippocampus development (P)||PMID:23351594||ECO:0000314 direct assay evidence used in manual assertion|
According to Figure 4A, B, in both the hippocampus and the hypothalamus regions of the tubby brain SSTR3 is essentially undetectable or greatly diminished.
|MOUSE:LMNB1||Abena.agyepong, Team Nucleus||2013-04-09 23:14:57 CDT||GO:0005635 nuclear envelope (C)||PMID:23166514||ECO:0000314 direct assay evidence used in manual assertion|
According to Figure 2, Lamin B1 shows variation in length of glutamic acid repeat, which greatly affects mobility within the nuclear envelope.
|MOUSE:Q05BI5||Abena.agyepong, Team Nucleus||2013-04-09 20:55:22 CDT||GO:0050673 epithelial cell proliferation (P)||PMID:23362346||ECO:0000315 mutant phenotype evidence used in manual assertion|
According to figure 3A and B, the proliferation of the putative TEC progenitors is independent of Cbx4.