User:Abena.agyepong

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
updatedbyinstructor	MOUSE:Q05BI5	2013-04-09 20:55:22 CDT	GO:0050673 epithelial cell proliferation (P)	PMID:23362346	ECO:0000315 mutant phenotype evidence used in manual assertion	According to figure 3A and B, the proliferation of the putative TEC progenitors is independent of Cbx4.	challenge
acceptable	MOUSE:LMNB1	2013-04-09 23:14:57 CDT	GO:0005635 nuclear envelope (C)	PMID:23166514	ECO:0000314 direct assay evidence used in manual assertion	According to Figure 2, Lamin B1 shows variation in length of glutamic acid repeat, which greatly affects mobility within the nuclear envelope.	challenge
requireschanges	MOUSE:TUB	2013-04-10 12:11:57 CDT	GO0021766 hippocampus development (P)	PMID:23351594	ECO:0000314 direct assay evidence used in manual assertion	According to Figure 4A, B, in both the hippocampus and the hypothalamus regions of the tubby brain SSTR3 is essentially undetectable or greatly diminished.	challenge
requireschanges	HUMAN:ZN330	2013-04-10 19:09:51 CDT	GO:0008104 protein localization (P)	PMID:23516598	ECO:0000314 direct assay evidence used in manual assertion	The nucleolar localization of Flag-NOA36 recombinant protein was confirmed using an anti-UBF antibody as nucleolar marker(Fig 2C. The nucleolar staining was not homogeneous, being localized mainly on the periphery of the nucleolus. From this data it is concluded that NOA36 contains at least one nucleolar localization signal.	challenge
acceptable	RAT:TGFB1	2013-04-11 13:39:00 CDT	GO:0006468 protein phosphorylation (P)	PMID:23393573	ECO:0000314 direct assay evidence used in manual assertion	According to Figure 8b, there was a 67%increase in phosphorylated FOXO1 in TGF- beta 1 treated cells compared to the levels in control treated cells. Moreover, Phosphorylation of FOXO1 in TGF-Beta 1 treated cells was inhibited in cells pretreated with P13K inhibitor.	challenge
updatedbyinstructor	HUMAN:COR1B	2013-04-13 18:13:49 CDT	GO:0030036 actin cytoskeleton organization (P)	PMID:18775315	ECO:0000314 direct assay evidence used in manual assertion	According to Figure 2C, in the presence of 50 nM Coronin 1B, total actin filament was reduced and branching was less extensive than in the control reactions.	challenge
acceptable	MOUSE:LEG3	2013-04-13 19:13:16 CDT	GO:0009986 cell surface (C)	PMID:23576987	ECO:0000314 direct assay evidence used in manual assertion	Gal-3 is known to be expressed on the cell surface of human Eos, but Mouse Eos express Gal-3 as well. Figure 2B shows cell surface expression of Gal-3 in non-permeabilized BM-derived Eos.	challenge
updatedbyinstructor	MOUSE:ALKB7	2013-04-13 21:14:48 CDT	GO:0005759 mitochondrial matrix (C)	PMID:23572141	ECO:0000314 direct assay evidence used in manual assertion	Figure 1 shows the subcellular localization of Alkbh7 in mouse.	challenge

acceptable:3
unacceptable:0
requires_changes:2
flagged:0

Annotations challenged by Abena.agyepong

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

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