GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

User:Schlangj

From GONUTS
Jump to: navigation, search

CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptable?2014-04-05 12:52:10 CDTGO:0008218 bioluminescence (Figure 3 shows the LuxR levels increase as the OD increases. This shows the connection between LuxR and high cell density. This implies that bioluminescence occurs when other organisms are present near by, verses when the surrounding area has low cell density.)PMID:23204455IDA: Inferred from Direct Assay
challenge
unacceptableECOLX:ROP2014-04-05 12:59:20 CDTGO:0017028 protein stabilization activity (F)PMID:18247355ECO:0000314 direct assay evidence used in manual assertion

Figure 3 shows that RNAI-RNAII dissociation is faster without the presence of Rop

challenge
unacceptableBPHK0:RPC32014-04-06 10:43:17 CDTGO:0019043 establishment of viral latency (P)PMID:17426811ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows that the levels of CII increase as the levels of CIII increase, which demonstrates that CIII can stabilize CII which then activates CI in order to establish lysogeny

challenge
unacceptableLAMBD:RPC22014-04-06 11:02:17 CDTGO:0016563 transcription activator activity (F)PMID:18298445ECO:0000314 direct assay evidence used in manual assertion

figure 2B shows the up regulation of CII as a heat shock response, which occurs so that transcription of CI can be activated and the cell can enter the lysogeny pathway

challenge
unacceptableLAMBD:RPC12014-04-06 11:13:58 CDTGO:0017053 transcriptional repressor complex (C)PMID:23853547ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows that there is a direct relationship between DNA looping and CI levels. This demonstrates how CI is a repressor protein.

challenge
unacceptableVIBHA:LUXO2014-04-06 11:30:42 CDTGO:0008218 bioluminescence (P)PMID:24698180ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 shows the LuxO is a bioluminescence repressor, by looking at a mutant that always has LuxO activated, and therefore bioluminescence does not occur.

challenge

acceptable:0
unacceptable:6
requires_changes:0
flagged:0

Annotations challenged by Schlangj

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableDjgulizia,
Team Texas Aggies
HUMAN:GOLP3GO:0005794 - Golgi apparatus (C)PMID:18410729ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
unacceptableRthompson,
Team Bfast Taco
HUMAN:PEPA5GO:0006508 - proteolysis (P)other:PMC1712889ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
unacceptableRthompson,
Team Bfast Taco
HUMAN:OPSDGO:0071482 - cellular response to light stimulus (P)PMID:8643442ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 4
unacceptableChong,
Team Kitten Me Right Meow
MOUSE:5HT2BGO:0008144 - obsolete drug binding (F)PMID:16940156ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
updatedbyinstructorKemmy,
Team GladSue
CHLRE:F6LJD1GO:1902326 - positive regulation of chlorophyll biosynthetic process (P)PMID:21527423ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1

0 annotations fixed by Schlangj

What do the icons mean in the status column?

assessment icons.jpg