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Category:Team GladSue

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHUMAN:ZBT16Kemmy, Team GladSue2014-03-02 15:14:07 CSTGO:0016604 nuclear body (C)PMID:24359566ECO:0000316 genetic interaction evidence used in manual assertion

Cellular localization of Znf179 was changed from cytoplasm to nucleus when PLZf was co-expressed. (Refer to Figure 4)

challenge
unacceptableHUMAN:MMP2Blondie, Team GladSue2014-02-27 10:20:45 CSTGO:0010467 gene expression (P)PMID:24551192ECO:0000314 direct assay evidence used in manual assertion

Figure 4. Levels of change in MMP2 expression by quantitative RT-PCR.

challenge
updatedbyinstructorCHLRE:F6LJD1Kemmy, Team GladSue2014-02-27 10:01:17 CSTGO:1902326 positive regulation of chlorophyll biosynthetic process (P)PMID:21527423ECO:0000315 mutant phenotype evidence used in manual assertion

CIA6 mutant increased chlorophyll content per cell. (refer to Figure 8)

challenge
unacceptableHUMAN:TGFB1Blondie, Team GladSue2014-02-27 09:56:56 CSTGO:0010467 gene expression (P)PMID:24551192ECO:0000314 direct assay evidence used in manual assertion

Figure 3. Vpu expressing monocytes show increased levels of TGF-β.

challenge
unacceptableHUMAN:VEGFCBlondie, Team GladSue2014-02-27 09:38:33 CSTGO:0010467 gene expression (P)PMID:24551192ECO:0000314 direct assay evidence used in manual assertion

Figure 1. Characterization of Vpu-expressing cell lines.

challenge
unacceptableHUMAN:GPR15Blondie, Team GladSue2014-02-27 09:29:38 CSTGO:0010467 gene expression (P)PMID:24558379ECO:0000314 direct assay evidence used in manual assertion

Uninfected or infected cells expressing GPR15, Fig 2

challenge
updatedbyinstructorHUMAN:G45IPKemmy, Team GladSue2014-02-27 08:47:58 CSTGO:0071850 mitotic cell cycle arrest (P)PMID:24520316ECO:0000314 direct assay evidence used in manual assertion

CRIF1 overexpression increased the proportion of jurkat cells arrested in G0/G1 while endogenous depletion decreased cell cycle arrest. (refer to Figure 3)

challenge
unacceptableHUMAN:CDC20Kemmy, Team GladSue2014-02-26 15:56:12 CSTGO:0010467 gene expression (P)PMID:24551295ECO:0000314 direct assay evidence used in manual assertion

There is upregulation of CDC20 mRNA in cancerous tissues than in noncancerous tissues (ref. figure 1). This upregulation of CDC20 is also associated with aggressive progression and poor prognosis in gastric cancer. (ref. figure 3).

challenge
unacceptableHUMAN:TERTKemmy, Team GladSue2014-02-26 14:47:14 CSTGO:0060218 hematopoietic stem cell differentiation (P)PMID:23585473ECO:0000315 mutant phenotype evidence used in manual assertion

Telomerase-mutant ipscs caused impaired hematopoietic differentiation in vitro. Ref to figure 6

challenge
unacceptableHUMAN:TERTKemmy, Team GladSue2014-02-25 01:48:29 CSTGO:0006915 apoptotic process (P)PMID:23326372ECO:0000314 direct assay evidence used in manual assertion

Nuclear localization of telomerase is correlated with higher amounts of DNA damage and apoptosis. (refer to Figure 2)

challenge

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Pages in category "Team GladSue"

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