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HUMAN:G45IP
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | GADD45GIP1 (synonyms: MRPL59, PLINP1, PRG6) | |
Protein Name(s) | Growth arrest and DNA damage-inducible proteins-interacting protein 1
39S ribosomal protein L59, mitochondrial MRP-L59 CKII beta-associating protein CR6-interacting factor 1 CRIF1 Papillomavirus L2-interacting nuclear protein 1 PLINP PLINP-1 p53-responsive gene 6 protein | |
External Links | ||
UniProt | Q8TAE8 | |
EMBL | AJ429498 AF479749 AF475095 BC004944 BC013039 BC013027 BC069200 AJ295986 AF147080 | |
CCDS | CCDS12290.1 | |
RefSeq | NP_443082.2 | |
UniGene | Hs.515164 | |
PDB | 3J7Y | |
PDBsum | 3J7Y | |
ProteinModelPortal | Q8TAE8 | |
BioGrid | 124721 | |
IntAct | Q8TAE8 | |
MINT | MINT-253595 | |
STRING | 9606.ENSP00000323065 | |
PhosphoSite | Q8TAE8 | |
DMDM | 74730346 | |
MaxQB | Q8TAE8 | |
PaxDb | Q8TAE8 | |
PeptideAtlas | Q8TAE8 | |
PRIDE | Q8TAE8 | |
DNASU | 90480 | |
Ensembl | ENST00000316939 | |
GeneID | 90480 | |
KEGG | hsa:90480 | |
UCSC | uc002mwb.4 | |
CTD | 90480 | |
GeneCards | GC19M013065 | |
HGNC | HGNC:29996 | |
MIM | 605162 | |
neXtProt | NX_Q8TAE8 | |
PharmGKB | PA134954784 | |
eggNOG | NOG285057 | |
GeneTree | ENSGT00390000013719 | |
HOGENOM | HOG000112686 | |
HOVERGEN | HBG068845 | |
InParanoid | Q8TAE8 | |
OMA | EQHIAEC | |
OrthoDB | EOG7ZKSDX | |
PhylomeDB | Q8TAE8 | |
TreeFam | TF323794 | |
Reactome | REACT_267602 REACT_267677 REACT_267680 | |
GeneWiki | GADD45GIP1 | |
GenomeRNAi | 90480 | |
NextBio | 76780 | |
PRO | PR:Q8TAE8 | |
Proteomes | UP000005640 | |
Bgee | Q8TAE8 | |
CleanEx | HS_GADD45GIP1 | |
ExpressionAtlas | Q8TAE8 | |
Genevestigator | Q8TAE8 | |
GO | GO:0005739 GO:0005634 GO:0007049 GO:0016032 | |
InterPro | IPR018472 | |
Pfam | PF10147 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0071850 |
mitotic cell cycle arrest |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
GO:0071850 |
mitotic cell cycle arrest |
ECO:0000314 |
P |
CRIF1 overexpression increased the proportion of jurkat cells arrested in G0/G1 while endogenous depletion decreased cell cycle arrest. (refer to Figure 3) |
complete | |||||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070126 |
mitochondrial translational termination |
Reactome:R-HSA-5419276 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070125 |
mitochondrial translational elongation |
Reactome:R-HSA-5389840 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005759 |
mitochondrial matrix |
Reactome:R-HSA-5419281 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005840 |
ribosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ran, Q et al. (2014) CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cells. PLoS ONE 9 e85328 PubMed GONUTS page