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HUMAN:GPR15
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | GPR15 | |
| Protein Name(s) | G-protein coupled receptor 15
Brother of Bonzo BoB | |
| External Links | ||
| UniProt | P49685 | |
| EMBL | U34806 BC069437 BC101779 BC101781 | |
| CCDS | CCDS2931.1 | |
| PIR | G02064 | |
| RefSeq | NP_005281.1 | |
| UniGene | Hs.563128 | |
| ProteinModelPortal | P49685 | |
| SMR | P49685 | |
| BioGrid | 109098 | |
| STRING | 9606.ENSP00000284311 | |
| PhosphoSite | P49685 | |
| DMDM | 1346170 | |
| PaxDb | P49685 | |
| PRIDE | P49685 | |
| DNASU | 2838 | |
| Ensembl | ENST00000284311 | |
| GeneID | 2838 | |
| KEGG | hsa:2838 | |
| UCSC | uc011bgy.3 | |
| CTD | 2838 | |
| GeneCards | GC03P098250 | |
| HGNC | HGNC:4469 | |
| HPA | HPA013775 | |
| MIM | 601166 | |
| neXtProt | NX_P49685 | |
| PharmGKB | PA28858 | |
| eggNOG | NOG148034 | |
| GeneTree | ENSGT00760000119055 | |
| HOGENOM | HOG000077773 | |
| HOVERGEN | HBG101112 | |
| InParanoid | P49685 | |
| KO | K08403 | |
| OMA | RRRDCAY | |
| OrthoDB | EOG73V6KF | |
| PhylomeDB | P49685 | |
| TreeFam | TF330024 | |
| GeneWiki | GPR15 | |
| GenomeRNAi | 2838 | |
| NextBio | 11197 | |
| PRO | PR:P49685 | |
| Proteomes | UP000005640 | |
| Bgee | P49685 | |
| CleanEx | HS_GPR15 | |
| ExpressionAtlas | P49685 | |
| Genevestigator | P49685 | |
| GO | GO:0005887 GO:0004930 GO:0007186 GO:0072678 | |
| InterPro | IPR000276 IPR017452 | |
| Pfam | PF00001 | |
| PRINTS | PR00237 | |
| PROSITE | PS00237 PS50262 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0010467 |
gene expression |
ECO:0000314 |
P |
Uninfected or infected cells expressing GPR15, Fig 2 |
complete | |||||
|
part_of |
GO:0005768 |
endosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015026 |
coreceptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001618 |
virus receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0025631 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1918473 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0072678 |
T cell migration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VDU3 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VDU3 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
Reactome:R-HSA-388396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-744887 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kiene, M et al. (2014) Toll-like receptor 3 signalling up-regulates expression of the HIV co-receptor G-protein coupled receptor 15 on human CD4+ T cells. PLoS ONE 9 e88195 PubMed GONUTS page
- ↑ 2.0 2.1 Okamoto, Y & Shikano, S (2017) Differential phosphorylation signals control endocytosis of GPR15. Mol. Biol. Cell 28 2267-2281 PubMed GONUTS page
- ↑ 3.0 3.1 Ocón, B et al. (2017) A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15. Front Immunol 8 1111 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Blaak, H et al. (2005) CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia. J. Virol. 79 1686-700 PubMed GONUTS page
- ↑ 5.0 5.1 Suply, T et al. (2017) A natural ligand for the orphan receptor GPR15 modulates lymphocyte recruitment to epithelia. Sci Signal 10 PubMed GONUTS page
- ↑ 6.0 6.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Heiber, M et al. (1996) A novel human gene encoding a G-protein-coupled receptor (GPR15) is located on chromosome 3. Genomics 32 462-5 PubMed GONUTS page
