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LAMBD:RPC1
Contents
Species (Taxon ID) | Escherichia phage lambda (Bacteriophage lambda). (10710) | |
Gene Name(s) | cI | |
Protein Name(s) | Repressor protein cI | |
External Links | ||
UniProt | P03034 | |
EMBL | J02459 X00166 | |
PIR | A14086 | |
RefSeq | NP_040628.1 | |
PDB | 1F39 1GFX 1J5G 1KCA 1LLI 1LMB 1LRP 1LWQ 1RIO 3BDN 3KZ3 3WOA | |
PDBsum | 1F39 1GFX 1J5G 1KCA 1LLI 1LMB 1LRP 1LWQ 1RIO 3BDN 3KZ3 3WOA | |
ProteinModelPortal | P03034 | |
SMR | P03034 | |
DIP | DIP-17006N | |
IntAct | P03034 | |
MEROPS | S24.002 | |
GeneID | 2703537 | |
KEGG | vg:3827059 | |
EvolutionaryTrace | P03034 | |
Proteomes | UP000001711 | |
GO | GO:0043565 GO:0006355 GO:0006351 | |
Gene3D | 1.10.260.40 2.10.109.10 | |
InterPro | IPR001387 IPR010982 IPR028360 IPR019759 IPR015927 | |
Pfam | PF01381 PF00717 | |
SMART | SM00530 | |
SUPFAM | SSF47413 SSF51306 | |
PROSITE | PS50943 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0017053 |
transcriptional repressor complex |
ECO:0000314 |
C |
Figure 5 shows that there is a direct relationship between DNA looping and CI levels. This demonstrates how CI is a repressor protein. |
complete | |||||
part_of |
GO:0019012 |
virion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019044 |
maintenance of viral latency |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010944 |
negative regulation of transcription by competitive promoter binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_regulation_target:(UniProtKB:P03034) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050434 |
positive regulation of viral transcription |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_regulation_target:(UniProtKB:P03034) |
Seeded From UniProt |
complete | ||
enables |
GO:0001047 |
core promoter binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019042 |
viral latency |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0098689 |
latency-replication decision |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Hensel, Z et al. (2013) Transcription-factor-mediated DNA looping probed by high-resolution, single-molecule imaging in live E. coli cells. PLoS Biol. 11 e1001591 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Schubert, RA et al. (2007) Cro's role in the CI Cro bistable switch is critical for {lambda}'s transition from lysogeny to lytic development. Genes Dev. 21 2461-72 PubMed GONUTS page
- ↑ Rajagopala, SV et al. (2011) The protein interaction map of bacteriophage lambda. BMC Microbiol. 11 213 PubMed GONUTS page
- ↑ Stayrook, S et al. (2008) Crystal structure of the lambda repressor and a model for pairwise cooperative operator binding. Nature 452 1022-5 PubMed GONUTS page