User:Rthompson

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
updatedbyinstructor	RAT:TAU	2014-01-29 20:56:19 CST	GO:0005874 microtubule (C)	PMID:1396588	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 shows that Tau was localized to microtubules using an anti-Tau and an anti-tubulin antibody.	challenge
unacceptable	HUMAN:PEPA5	2014-01-31 15:35:24 CST	GO:0006508 proteolysis (P)	other:PMC1712889	ECO:0000314 direct assay evidence used in manual assertion	he techniques of starch gel electrophoresis, immunoelectrophoresis and high resolutiongelfiltrationhavebeenusedtoinvestigatethepepticcleavageofhuman G-myeloma proteins of the four known subclasses.	challenge
unacceptable	HUMAN:PROC	2014-01-31 15:50:51 CST	GO:0030195 negative regulation of blood coagulation (P)	PMID:9529319	ECO:0000304 author statement supported by traceable reference used in manual assertion	EPCR enables significant levels of protein C activation. These results suggest that the protein C anticoagulation pathway is important for the regulation of blood coagulation not only in microvessels but also in large vessels.	challenge
unacceptable	HUMAN:OPSD	2014-01-31 16:06:19 CST	GO:0071482 cellular response to light stimulus (P)	PMID:8643442	ECO:0000315 mutant phenotype evidence used in manual assertion	Comparisons between the mutant, incorrectly folded Rhodopsin and the correctly folded Rhodopsin resulted in a negative influence on the ability to interpret a light stimulus.	challenge
unacceptable	HUMAN:TARA	2014-02-02 17:10:26 CST	GO:0015629 actin cytoskeleton (C)	PMID:9190212	ECO:0000314 direct assay evidence used in manual assertion	In this study, the role of the cytoskeleton in LFA-1 activation and demonstrate that filamentous actin (F-actin) was shown to both enhance and inhibit LFA-1-mediated adhesion, depending on the distribution of LFA-1 on the cell surface.	challenge

acceptable:0
unacceptable:4
requires_changes:0
flagged:0

Annotations challenged by Rthompson

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
unacceptable	Gandii2, Team Protein Titans	GIAIA:E1F6D1	GO:0060627 - regulation of vesicle-mediated transport (P)	PMID:20532229	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 6
unacceptable	Sprem, Team On a Boat	HUMAN:HXK1	GO:0004396 - hexokinase activity (F)	PMID:9531504	ECO:0000255 match to sequence model evidence used in manual assertion	challenge	C: 3
updatedbyinstructor	Aross, Team BAMF	DROME:ABL	GO:0010592 - positive regulation of lamellipodium assembly (P)	PMID:24466097	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 4
unacceptable	Kgoldthorn, Team Takin This Outside	ECO57:TUS	GO:0003677 - DNA binding (F)	PMID:11206551	ECO:0000317 genomic context evidence used in manual assertion	challenge	C: 2
unacceptable	Sirons, Team Takin This Outside	HUMAN:TTBK1	GO:0005737 - cytoplasm (C)	PMID:17344846	ECO:0000247 sequence alignment evidence used in manual assertion	challenge	C: 2

0 annotations fixed by Rthompson

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